Bifenox

Bifenox

SCHEMBL27552005

COC(=O)c1cc(Oc2ccc(Cl)cc2Cl)ccc1[N+](=O)[O-].O=[N+]([O-])c1ccc(Oc2ccc(Cl)cc2Cl)cc1

nearest known ligand 0.89

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.89
MEN1 O00255 5/20 0.53
KMT2A Q03164 5/20 0.53
GAA P10253 1/20 0.53
PKM P14618 1/20 0.53
TTR P02766 1/20 0.52
PPOX P50336 1/20 0.52
ALDH1A1 P00352 7/20 0.49
MAPT P10636 6/20 0.49
LMNA P02545 4/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
PDE7A Q13946 2/20 0.48
TBXA2R P21731 1/20 0.46
PYGL P06737 1/20 0.45
NPSR1 Q6W5P4 2/20 0.44
HPGD P15428 1/20 0.44
PLA2G1B P04054 1/20 0.44
ATG4B Q9Y4P1 1/20 0.44
HSP90AA1 P07900 1/20 0.43
POLB P06746 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bifenox SCHEMBL30862569 0.94 TDP1 (1.00) TDP1MEN1KMT2AGAAPKM
Bifenox SCHEMBL8541647 0.94 TDP1 (1.00) TDP1MEN1KMT2AGAAPKM
Bifenox SCHEMBL38816 0.94 TDP1 (1.00) TDP1MEN1KMT2AGAAPKM
Bifenox SCHEMBL28419037 0.93 TDP1 (0.98) TDP1MEN1KMT2AGAAPKM
SCHEMBL10789320 0.91 TDP1 (0.81) TDP1MEN1KMT2AGAAPKM
Bifenox SCHEMBL9427378 0.87 TDP1 (0.84) TDP1MEN1KMT2ATTRPPOX
Bifenox SCHEMBL9129964 0.87 TDP1 (0.84) TDP1MEN1KMT2ATTRPPOX
Bifenox SCHEMBL21816747 0.87 TDP1 (0.84) TDP1MEN1KMT2ATTRPPOX
Bifenox SCHEMBL9427373 0.87 TDP1 (0.84) TDP1MEN1KMT2ATTRPPOX
SCHEMBL10789757 0.87 TDP1 (0.84) TDP1MEN1KMT2ATTRPPOX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1189763-A Herbicidal compositions comprising 4-iodo-2- [ 3- (4-methoxy-6-methyl-1, 3, 5-triazin-2-yl) ureidosulfonyl ] benzoates HOECHST SCHERING AGREVO GMBH (DE) 1998-08-05 CN claimed
CN-1189763-A Herbicidal compositions comprising 4-iodo-2- [ 3- (4-methoxy-6-methyl-1, 3, 5-triazin-2-yl) ureidosulfonyl ] benzoates HOECHST SCHERING AGREVO GMBH (DE) 1998-08-05 CN disclosed