Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 9/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.50 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27476902 | 0.90 | TSHR (0.62) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL2367697 | 0.89 | TSHR (0.60) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL26979856 | 0.88 | TSHR (0.57) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL27559160 | 0.87 | TSHR (0.58) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| Acrylic Acid SCHEMBL9324158 | 0.86 | TSHR (0.54) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| Isobutane SCHEMBL28133828 | 0.86 | TSHR (0.75) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| Isobutane SCHEMBL23794926 | 0.84 | TSHR (0.78) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL811560 | 0.84 | TSHR (0.84) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL10868277 | 0.84 | TSHR (0.84) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL22607678 | 0.84 | TSHR (0.84) | TSHRHPGDALDH1A1CYP3A4HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1190477-C | Lubrication oil for refrigerator, hydraulic fluid compoistion for refrigerator and method for lubrication of refrigerator | NEW JAPAN CHEMICALS CO LTD (JP) | 2005-02-23 | — | — | CN | disclosed |
| CN-1349555-A | Lubrication oil for refrigerator, hydraulic fluid compoistion for refrigerator and method for lubrication of refrigerator | NEW JAPAN CHEMICALS CO LTD (JP) | 2002-05-15 | — | — | CN | disclosed |