SCHEMBL27552155

SCHEMBL27552155

CC=CC=Cc1ccccc1.[Ti]

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.70
TRPA1 O75762 3/20 0.52
MAPK1 P28482 2/20 0.52
ALDH1A1 P00352 1/20 0.52
LMNA P02545 1/20 0.52
ALOX5 P09917 1/20 0.52
CYP3A4 P08684 1/20 0.46
HDAC3 O15379 1/20 0.45
HDAC4 P56524 1/20 0.45
HDAC1 Q13547 1/20 0.45
HDAC7 Q8WUI4 1/20 0.45
HDAC2 Q92769 1/20 0.45
HDAC10 Q969S8 1/20 0.45
HDAC11 Q96DB2 1/20 0.45
HDAC8 Q9BY41 1/20 0.45
HDAC6 Q9UBN7 1/20 0.45
HDAC9 Q9UKV0 1/20 0.45
HDAC5 Q9UQL6 1/20 0.45
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21457949 0.97 MAOB (0.74) MAOBTRPA1MAPK1ALDH1A1LMNA
SCHEMBL9454821 0.97 MAOB (0.74) MAOBTRPA1MAPK1ALDH1A1LMNA
SCHEMBL627660 0.97 MAOB (0.74) MAOBTRPA1MAPK1ALDH1A1LMNA
SCHEMBL627659 0.97 MAOB (0.74) MAOBTRPA1MAPK1ALDH1A1LMNA
SCHEMBL16867382 0.95 MAOB (0.70) MAOBTRPA1MAPK1ALDH1A1LMNA
SCHEMBL11262511 0.95 MAOB (0.70) MAOBTRPA1MAPK1ALDH1A1LMNA
SCHEMBL504509 0.95 MAOB (0.70) MAOBTRPA1MAPK1ALDH1A1LMNA
SCHEMBL11262494 0.95 MAOB (0.70) MAOBTRPA1MAPK1ALDH1A1LMNA
SCHEMBL27493157 0.95 MAOB (0.70) MAOBTRPA1MAPK1ALDH1A1LMNA
SCHEMBL27478248 0.95 MAOB (0.70) MAOBTRPA1MAPK1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1192033-C Bridged metal complexes DOW CHEMICAL CO (US) 2005-03-09 CN disclosed
CN-1322208-A Bridged metal complexes DOW CHEMICAL CO (US) 2001-11-14 CN disclosed