Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | GGT1 | P19440 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | CPT2 | P23786 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22549656 | 0.85 | — | — | |
| Bromide SCHEMBL27450868 | 0.79 | — | — | |
| SCHEMBL84219 | 0.78 | — | — | |
| SCHEMBL1133260 | 0.78 | — | — | |
| SCHEMBL690783 | 0.78 | — | — | |
| SCHEMBL10702393 | 0.78 | — | — | |
| SCHEMBL18641319 | 0.77 | HMGCR (0.32) | HMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL22664246 | 0.75 | KDM4E (0.33) | HMGCRCHRM1TBXA2RADRA1AKDM4E | |
| Hydrochloric Acid SCHEMBL14889588 | 0.75 | — | — | |
| SCHEMBL22458268 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1332958-C | Process for producing n-monoalkyl-3-hydroxy-3-(2-thienyl)propanamine and intermediate | SUMITOMO SEIKA CHEMICALS (JP) | 2007-08-22 | — | — | CN | disclosed |
| CN-1671686-A | Process for producing n-monoalkyl-3-hydroxy-3-(2-thienyl)propanamine and intermediate | SUMITOMO SEIKA CHEMICALS (JP) | 2005-09-21 | — | — | CN | disclosed |