Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | ESR1 | P03372 | 3/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.52 |
| ▸ | TACR2 | P21452 | 2/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.52 |
| ▸ | SHBG | P04278 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.52 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4860981 | 1.00 | HIF1A (0.52) | HIF1AKDM4EESR1ADORA3SLC6A2 | |
| SCHEMBL27981045 | 1.00 | HIF1A (0.52) | HIF1AKDM4EESR1ADORA3SLC6A2 | |
| SCHEMBL10457370 | 1.00 | HIF1A (0.52) | HIF1AKDM4EESR1ADORA3SLC6A2 | |
| SCHEMBL12087597 | 1.00 | HIF1A (0.52) | HIF1AKDM4EESR1ADORA3SLC6A2 | |
| SCHEMBL9121212 | 0.98 | TAAR1 (0.52) | HIF1AKDM4EESR1ADORA3SLC6A2 | |
| SCHEMBL22034389 | 0.94 | HIF1A (0.47) | HIF1AKDM4EESR1ADORA3SLC6A2 | |
| SCHEMBL22034390 | 0.94 | HIF1A (0.47) | HIF1AKDM4EESR1ADORA3SLC6A2 | |
| SCHEMBL4625231 | 0.92 | TAAR1 (0.54) | HIF1AKDM4EESR1ADORA3SLC6A2 | |
| SCHEMBL7066863 | 0.87 | TAAR1 (0.62) | HIF1AKDM4EESR1ADORA3SLC6A2 | |
| SCHEMBL8092484 | 0.87 | ESR1 (0.46) | HIF1AKDM4EESR1ADORA3SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113549606-A | Alpha-amylase variants with altered properties | 诺维信公司 | 2021-10-26 | — | — | CN | disclosed |
| CN-107151662-B | Alpha-amylase variants with altered properties | 诺维信公司 | 2021-06-29 | — | — | CN | disclosed |
| CN-102471244-B | Process for producing N-substituted carbamate, process for producing isocyanate using the N-substituted carbamate, and composition for transporting and storing N-substituted carbamate containing N-substituted carbamate and aromatic hydroxy compound | ASAHI CHEMICAL CORP | 2014-09-24 | — | — | CN | disclosed |
| CN-1196334-A | Method for preparing cation/amphoteric graft polyacrylamide flocculating agent | GUANGZHOU CITY ENVIRONMENTAL P (CN) | 1998-10-21 | — | — | CN | disclosed |