Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Palmitaldehyde. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.80 |
| ▸ | FAAH | O00519 | 3/20 | 0.70 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.70 |
| ▸ | TERT | O14746 | 3/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.48 |
| ▸ | PPARG | P37231 | 3/20 | 0.48 |
| ▸ | PPARD | Q03181 | 3/20 | 0.48 |
| ▸ | PPARA | Q07869 | 3/20 | 0.48 |
| ▸ | TOP1 | P11387 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | BLM | P54132 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | FABP4 | P15090 | 2/20 | 0.48 |
| ▸ | GMNN | O75496 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Decanal SCHEMBL28505277 | 0.97 | TSHR (0.84) | TSHRFAAHTRPV1HSD17B10LMNA | |
| Tridecanal SCHEMBL29019017 | 0.97 | TSHR (0.84) | TSHRFAAHTRPV1HSD17B10LMNA | |
| Nonanal SCHEMBL2352897 | 0.97 | TSHR (0.84) | TSHRFAAHTRPV1HSD17B10LMNA | |
| Octanal SCHEMBL8439593 | 0.97 | TSHR (0.84) | TSHRFAAHTRPV1HSD17B10LMNA | |
| Hexanal SCHEMBL28119013 | 0.95 | TSHR (0.79) | TSHRFAAHTRPV1MAPTBLM | |
| Octanal SCHEMBL2453523 | 0.90 | TSHR (0.80) | TSHRFAAHTRPV1HSD17B10LMNA | |
| Tridecanal SCHEMBL9083185 | 0.90 | TSHR (0.80) | TSHRFAAHTRPV1HSD17B10LMNA | |
| Palmitaldehyde SCHEMBL6162415 | 0.90 | TSHR (0.80) | TSHRFAAHTRPV1HSD17B10LMNA | |
| Heptanal SCHEMBL2454694 | 0.90 | TSHR (0.80) | TSHRFAAHTRPV1HSD17B10LMNA | |
| Octanal SCHEMBL27493183 | 0.90 | TSHR (0.89) | TSHRFAAHTRPV1MAPTBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1385457-A | Gel composition | PANRICO PARTNERSHIP INC (US) | 2002-12-18 | — | — | CN | disclosed |
| CN-1348815-A | Medicine for preventing and treating coronary heart disease and angina pectoris and its prepn and other use | TIANJIN TIANSHILI PHARMACEUTIC (CN) | 2002-05-15 | — | — | CN | disclosed |