Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.38 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.38 |
| ▸ | RARB | P10826 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | DGKA | P23743 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28016187 | 1.00 | TSHR (0.43) | TSHRKDM4CKDM4APHF8KDM2A | |
| SCHEMBL27518791 | 1.00 | TSHR (0.43) | TSHRKDM4CKDM4APHF8KDM2A | |
| SCHEMBL28591823 | 1.00 | TSHR (0.43) | TSHRKDM4CKDM4APHF8KDM2A | |
| SCHEMBL27626098 | 1.00 | TSHR (0.43) | TSHRKDM4CKDM4APHF8KDM2A | |
| SCHEMBL27646584 | 0.97 | TSHR (0.43) | TSHRKDM4CKDM4APHF8KDM2A | |
| SCHEMBL18815161 | 0.94 | TSHR (0.54) | TSHRNAAADGKANPSR1 | |
| SCHEMBL28365030 | 0.94 | TSHR (0.54) | TSHRNAAADGKANPSR1 | |
| SCHEMBL27646653 | 0.94 | TSHR (0.54) | TSHRNAAADGKANPSR1 | |
| SCHEMBL9929476 | 0.94 | TSHR (0.54) | TSHRNAAADGKANPSR1 | |
| SCHEMBL27962621 | 0.94 | TSHR (0.54) | TSHRNAAADGKANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1385457-A | Gel composition | PANRICO PARTNERSHIP INC (US) | 2002-12-18 | — | — | CN | disclosed |
| CN-1348815-A | Medicine for preventing and treating coronary heart disease and angina pectoris and its prepn and other use | TIANJIN TIANSHILI PHARMACEUTIC (CN) | 2002-05-15 | — | — | CN | disclosed |