Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 9/20 | 0.43 |
| ▸ | PTPRC | P08575 | 2/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.36 |
| ▸ | PTPRB | P23467 | 2/20 | 0.36 |
| ▸ | PTPRE | P23469 | 2/20 | 0.36 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6402782 | 0.89 | PTPN1 (0.57) | PTPN1PTPRCPTPN2PTPRBPTPRE | |
| SCHEMBL7693899 | 0.83 | PTPN1 (0.53) | PTPN1PTPRCPTPN2PTPRBPTPRE | |
| SCHEMBL7854135 | 0.80 | PTPN1 (0.58) | PTPN1PTPRCPTPN2PTPRBPTPRE | |
| SCHEMBL7688988 | 0.79 | PTPN1 (0.55) | PTPN1PTPRCPTPN2PTPRBPTPRE | |
| SCHEMBL4449756 | 0.79 | PTPN1 (0.55) | PTPN1PTPRCPTPN2PTPRBPTPRE | |
| SCHEMBL7855098 | 0.79 | PTPN2 (0.58) | PTPN1PTPN2KMT2ANOD1POLB | |
| SCHEMBL6399832 | 0.77 | PTPN1 (0.39) | PTPN1PTPRCPTPN2PTPRBPTPRE | |
| SCHEMBL7562771 | 0.75 | PTPN1 (0.35) | PTPN1PTPRCPTPN2PTPRBPTPRE | |
| SCHEMBL7855558 | 0.75 | KMT2A (0.53) | PTPN1PTPN2KMT2ANOD1POLB | |
| SCHEMBL7696216 | 0.71 | GRM1 (0.48) | PTPN1PTPN2KMT2ANOD1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1300291-A | Modulators of protein tyrosine phosphatases (PTP enzymes) | NOVO NORDISK AS (DK) | 2001-06-20 | — | — | CN | claimed |
| CN-1300291-A | Modulators of protein tyrosine phosphatases (PTP enzymes) | NOVO NORDISK AS (DK) | 2001-06-20 | — | — | CN | disclosed |