Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.34 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.34 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4720632 | 0.80 | HDAC1 (0.51) | KDM4EALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL1641523 | 0.80 | HDAC1 (0.52) | KDM4EALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL9232392 | 0.79 | PTGS1 (0.41) | KDM4EALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL5470951 | 0.76 | BACE1 (0.51) | KDM4EMEN1KMT2AAKR1B1 | |
| SCHEMBL140815 | 0.75 | CYP1A2 (0.65) | KDM4EALDH1A1MEN1KMT2ACYP1A2 | |
| Anthracene SCHEMBL10418177 | 0.75 | CYP1A2 (0.59) | KDM4EALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL20480384 | 0.72 | CAMK2A (0.42) | ALDH1A1MEN1KMT2ACYP1A2AKR1B1 | |
| SCHEMBL6352993 | 0.72 | CYSLTR1 (0.44) | KDM4EALDH1A1CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL6300146 | 0.71 | KMT2A (0.47) | KDM4EALDH1A1MEN1KMT2ACYP1A2 | |
| Acetic Acid SCHEMBL27459479 | 0.71 | CYP1A2 (0.64) | KDM4EALDH1A1MEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101074242-A | Cells accumulation for sphosphonate analogs of HIV protease inhibitor compound and the same compound | GILEAD SCIENCES INC (US) | 2007-11-21 | — | — | CN | disclosed |
| CN-1313472-C | Cellular Accumulation of Phosphonate Analogs of HIV Protease Inhibitor Compounds and Such Compounds | GILEAD SCIENCES INC (US) | 2007-05-02 | — | — | CN | disclosed |
| CN-1649885-A | Cellular Accumulation of Phosphonate Analogs of HIV Protease Inhibitor Compounds and Such Compounds | GILEAD SCIENCES INC (US) | 2005-08-03 | — | — | CN | disclosed |