SCHEMBL27559656

SCHEMBL27559656

CCCCCCCCCCCCCCCCCCC(C)(CCC)CCCCCCCCCCCCCCCCCC

nearest known ligand 0.47

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.47
THRB P10828 1/20 0.47
GGPS1 O95749 6/20 0.41
FDPS P14324 9/20 0.39
SMPD1 P17405 2/20 0.38
CES2 O00748 1/20 0.38
LPAR1 Q92633 1/20 0.38
LPAR3 Q9UBY5 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27906995 1.00 TSHR (0.47) TSHRTHRBGGPS1FDPSSMPD1
SCHEMBL3630817 1.00 TSHR (0.47) TSHRTHRBGGPS1FDPSSMPD1
SCHEMBL28021411 1.00 TSHR (0.47) TSHRTHRBGGPS1FDPSSMPD1
SCHEMBL28075094 1.00 TSHR (0.47) TSHRTHRBGGPS1FDPSSMPD1
SCHEMBL3634312 1.00 TSHR (0.47) TSHRTHRBGGPS1FDPSSMPD1
SCHEMBL5070252 0.94 TSHR (0.39) TSHRTHRBGGPS1FDPSSMPD1
SCHEMBL8687541 0.94 TSHR (0.53) TSHRTHRBGGPS1FDPSSMPD1
SCHEMBL8686371 0.94 TSHR (0.53) TSHRTHRBGGPS1FDPSSMPD1
SCHEMBL8684913 0.94 TSHR (0.53) TSHRTHRBGGPS1FDPSSMPD1
SCHEMBL8690214 0.94 TSHR (0.53) TSHRTHRBGGPS1FDPSSMPD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109528686-A Utilize the polymer-lipid mixing nano particle of microring array and the capecitabine of capecitabine amphipathic characteristic 杭州景杰生物科技有限公司 2019-03-29 CN claimed
CN-101252940-A External composition for improving skin diseases comprising adenosyl cobalamin KOREA RES INST CHEM TECH (KR) 2008-08-27 CN claimed
CN-105658243-B Ultrasound mediated drug delivery 菲尼克斯解决方案有限公司 2019-11-08 CN disclosed
CN-110352071-A Lipidic nanoparticles mRNA vaccine 库瑞瓦格股份公司 2019-10-18 CN disclosed
CN-105163720-B Remote loading sparingly water-soluble drug is to liposome 佐尼奥尼制药股份有限公司 2019-10-11 CN disclosed
CN-105873568-B Tool for lung specificity delivering 赛伦斯治疗有限公司 2019-10-08 CN disclosed
CN-110302162-A Modularization particle for immunotherapy 耶鲁大学 2019-10-08 CN disclosed
CN-110251463-A Lotion containing hormone 贝朗医疗有限公司 2019-09-20 CN disclosed
CN-105848649-B modular particles for immunotherapy 耶鲁大学 2019-08-02 CN disclosed
CN-110003030-A Trialkyl cation lipid and its application method 野草莓树生物制药公司 2019-07-12 CN disclosed
CN-109922808-A Liposome formulations for the treatment of cancer 法国施维雅药厂 2019-06-21 CN disclosed
CN-101291678-A Carrier composition for nucleic acid transfer OTSUKA PHARMA CO LTD (JP) 2008-10-22 CN disclosed
CN-101252940-A External composition for improving skin diseases comprising adenosyl cobalamin KOREA RES INST CHEM TECH (KR) 2008-08-27 CN disclosed
CN-1915968-A Neutral-cationic lipid for nucleic acid and drug delivery ALZA CORP (US) 2007-02-21 CN disclosed
CN-1732960-A As suppressing the HIV-1 trans-activator combines usefulness with the trans-activating response sequence RNA phosphatidyl ethanolamine liposome CHINESE ACAD INST CHEMISTRY (CN) 2006-02-15 CN disclosed
CN-1387505-A Compositions contg. hydroxyeicosatetraenoic acid derivs, and methods of use in treating dry eye disorders ALCON UNIVERSAL LTD (CH) 2002-12-25 CN disclosed
CN-1387502-A 15-hydroxyeicosatetraenoic acid-related compounds and methods of use ALCON UNIVERSAL LTD (CH) 2002-12-25 CN disclosed
CN-1387435-A Lipoxin A for the treatment of dry eye4And derivatives thereof ALCON UNIVERSAL LTD (CH) 2002-12-25 CN disclosed
CN-1382046-A Heteroatom-inserted analogs of 15-hydroxyeicosatetraenoic acid and methods of use ALCON UNIVERSAL LTD (CH) 2002-11-27 CN disclosed
CN-1378536-A Neutral-cationic lipids for nucleic acid and drug delivery ALZA CORP (US) 2002-11-06 CN disclosed