Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 2/20 | 0.48 |
| ▸ | LCK | P06239 | 9/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.46 |
| ▸ | MAPK13 | O15264 | 4/20 | 0.45 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | LYN | P07948 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | AKT2 | P31751 | 1/20 | 0.45 |
| ▸ | FLT4 | P35916 | 1/20 | 0.45 |
| ▸ | FLT3 | P36888 | 1/20 | 0.45 |
| ▸ | FRK | P42685 | 1/20 | 0.45 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.45 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.45 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.45 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.45 |
| ▸ | GSK3A | P49840 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.45 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6982124 | 1.00 | IDH1 (0.48) | IDH1LCKMAPK14MAPK13PRKD3 | |
| SCHEMBL27581646 | 0.89 | LCK (0.53) | IDH1LCKMAPK14MAPK13PRKD3 | |
| SCHEMBL6981895 | 0.89 | LCK (0.53) | IDH1LCKMAPK14MAPK13PRKD3 | |
| SCHEMBL6983442 | 0.88 | IDH1 (0.48) | IDH1LCKMAPK14MAPK13PRKD3 | |
| SCHEMBL27560949 | 0.88 | IDH1 (0.48) | IDH1LCKMAPK14MAPK13PRKD3 | |
| SCHEMBL27560843 | 0.87 | LCK (0.57) | IDH1LCKMAPK14MAPK13PRKD3 | |
| SCHEMBL6985098 | 0.87 | LCK (0.57) | IDH1LCKMAPK14MAPK13PRKD3 | |
| SCHEMBL27581600 | 0.86 | LCK (0.52) | IDH1LCKMAPK14MAPK13PRKD3 | |
| SCHEMBL6986643 | 0.86 | LCK (0.52) | IDH1LCKMAPK14MAPK13PRKD3 | |
| SCHEMBL6984979 | 0.86 | IDH1 (0.48) | IDH1LCKMAPK14MAPK13PRKD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1378544-A | Substituted azoles compounds | NOVARTIS AG (CH) | 2002-11-06 | — | — | CN | claimed |
| CN-1378544-A | Substituted azoles compounds | NOVARTIS AG (CH) | 2002-11-06 | — | — | CN | disclosed |