Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | PRNP | P04156 | 1/20 | 0.41 |
| ▸ | FABP4 | P15090 | 2/20 | 0.41 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | MPL | P40238 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | STAT6 | P42226 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7202860 | 0.84 | HSD17B10 (0.50) | CYP1A2HSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL16874351 | 0.81 | CYP2D6 (0.50) | CYP1A2HSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL1940101 | 0.76 | CYP1A2 (0.63) | CYP1A2HSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL11300699 | 0.76 | MPL (0.45) | CYP1A2HSD17B10MEN1KMT2ACYP2D6 | |
| SCHEMBL9996096 | 0.75 | PRNP (0.54) | CYP1A2HSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL1039306 | 0.75 | CYP1A2 (0.61) | CYP1A2HSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL4368303 | 0.75 | MCL1 (0.51) | CYP1A2HSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL1039309 | 0.75 | CYP1A2 (0.61) | CYP1A2HSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL9780384 | 0.74 | TTR (0.50) | CYP1A2ALDH1A1MEN1KMT2ACYP2C19 | |
| SCHEMBL7670398 | 0.74 | MEN1 (0.46) | CYP1A2HSD17B10ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1309638-A | N-substituted naphthamides as neurokinin receptor antagonists | ASTRAZENECA AB (SE) | 2001-08-22 | — | — | CN | disclosed |