Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 3/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.54 |
| ▸ | CHRM3 | P20309 | 12/20 | 0.53 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.53 |
| ▸ | HRH1 | P35367 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | HRH2 | P25021 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.53 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.53 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9922432 | 0.93 | CHRM2 (0.62) | CHRM2CHRM1CHRM3CHRM5HRH1 | |
| SCHEMBL2166483 | 0.93 | CHRM2 (0.62) | CHRM2CHRM1CHRM3CHRM5HRH1 | |
| SCHEMBL27491763 | 0.90 | CHRM3 (0.51) | CHRM2CHRM1CHRM3CHRM5HRH1 | |
| SCHEMBL27491764 | 0.89 | CHRM3 (0.50) | CHRM2CHRM1CHRM3CHRM5HRH1 | |
| SCHEMBL27508032 | 0.87 | CHRM3 (0.57) | CHRM2CHRM1CHRM3CHRM5HRH1 | |
| SCHEMBL27491770 | 0.86 | CHRM2 (0.58) | CHRM2CHRM1CHRM3CHRM5HRH1 | |
| SCHEMBL27505251 | 0.85 | CHRM3 (0.55) | CHRM2CHRM1CHRM3CHRM5HRH1 | |
| SCHEMBL5178337 | 0.84 | CHRM3 (0.61) | CHRM2CHRM1CHRM3CHRM5HRH1 | |
| SCHEMBL11295361 | 0.84 | CHRM3 (0.62) | CHRM2CHRM1CHRM3CHRM5HRH1 | |
| SCHEMBL8432689 | 0.84 | CHRM3 (0.62) | CHRM2CHRM1CHRM3CHRM5HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1207268-C | 3, 3-diphenylpropylamine derivatives | SANOL ARZNEI SCHWARZ GMBH (DE) | 2005-06-22 | — | — | CN | claimed |
| CN-1354737-A | Novel 3, 3-diphenylpropylamine derivatives | SANOL ARZNEI SCHWARZ GMBH (DE) | 2002-06-19 | — | — | CN | claimed |
| CN-100491336-C | Novel derivatives of 3,3-diphenylpropylamines | SANOL ARZNEI SCHWARZ GMBH (DE) | 2009-05-27 | — | — | CN | disclosed |
| CN-1690041-A | Novel derivatives of 3,3-diphenylpropylamines | SANOL ARZNEI SCHWARZ GMBH (DE) | 2005-11-02 | — | — | CN | disclosed |
| CN-1207268-C | 3, 3-diphenylpropylamine derivatives | SANOL ARZNEI SCHWARZ GMBH (DE) | 2005-06-22 | — | — | CN | disclosed |
| CN-1354737-A | Novel 3, 3-diphenylpropylamine derivatives | SANOL ARZNEI SCHWARZ GMBH (DE) | 2002-06-19 | — | — | CN | disclosed |