Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRK2 | P25098 | 1/20 | 0.71 |
| ▸ | CASP6 | P55212 | 1/20 | 0.71 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.71 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.71 |
| ▸ | APEX1 | P27695 | 1/20 | 0.71 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.69 |
| ▸ | GAA | P10253 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 3/20 | 0.66 |
| ▸ | NPC1 | O15118 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | GLA | P06280 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12172851 | 0.85 | NPSR1 (0.57) | GRK2CASP6CASP8CTDSP1TDP1 | |
| SCHEMBL24283827 | 0.84 | NPSR1 (0.68) | GRK2CASP6CASP8CTDSP1TDP1 | |
| SCHEMBL7814275 | 0.84 | GRK2 (0.72) | GRK2CASP6CASP8CTDSP1TDP1 | |
| SCHEMBL7814995 | 0.83 | HTT (0.71) | GRK2CASP6CASP8CTDSP1TDP1 | |
| SCHEMBL13920562 | 0.82 | NPSR1 (1.00) | NPSR1GAAALDH1A1RAB9ANPC1 | |
| SCHEMBL15503788 | 0.81 | GAA (1.00) | GRK2CASP6CASP8CTDSP1TDP1 | |
| SCHEMBL259424 | 0.81 | NPSR1 (0.97) | NPSR1GAAALDH1A1TP53RAB9A | |
| SCHEMBL20339082 | 0.79 | MAPT (0.67) | ALDH1A1TP53RAB9ANPC1MAPT | |
| SCHEMBL21577925 | 0.79 | MAPT (0.69) | ALDH1A1TP53RAB9ANPC1MAPT | |
| SCHEMBL12764072 | 0.79 | NPSR1 (0.94) | NPSR1GAAALDH1A1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1314906-A | Salts of paroxetine | SMITHKLINE BEECHAM PLC (GB) | 2001-09-26 | — | — | CN | disclosed |