Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 20/20 | 0.57 |
| ▸ | F10 | P00742 | 19/20 | 0.57 |
| ▸ | PRSS1 | P07477 | 19/20 | 0.57 |
| ▸ | F3 | P13726 | 17/20 | 0.57 |
| ▸ | PRSS2 | P07478 | 16/20 | 0.57 |
| ▸ | PRSS3 | P35030 | 16/20 | 0.57 |
| ▸ | F2 | P00734 | 17/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5882912 | 0.82 | F7 (0.66) | F7F10PRSS1F3PRSS2 | |
| Hydrochloric Acid SCHEMBL5882704 | 0.82 | F7 (0.65) | F7F10PRSS1F3PRSS2 | |
| SCHEMBL5882960 | 0.79 | F7 (0.60) | F7F10PRSS1F3PRSS2 | |
| Hydrochloric Acid SCHEMBL5882485 | 0.78 | F7 (0.59) | F7F10PRSS1F3PRSS2 | |
| SCHEMBL5882591 | 0.78 | F7 (0.59) | F7F10PRSS1F3PRSS2 | |
| Hydrochloric Acid SCHEMBL5882998 | 0.74 | F7 (0.74) | F7F10PRSS1F3PRSS2 | |
| SCHEMBL5882795 | 0.74 | F7 (0.68) | F7F10PRSS1F3PRSS2 | |
| Hydrochloric Acid SCHEMBL5882665 | 0.74 | F7 (0.67) | F7F10PRSS1F3PRSS2 | |
| SCHEMBL13161840 | 0.74 | F7 (0.64) | F7F10PRSS1F3PRSS2 | |
| Hydrochloric Acid SCHEMBL5882230 | 0.74 | F7 (0.63) | F7F10PRSS1F3PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1245381-C | Phenylglycine derivatives | HOFFMANN LA ROCHE (CH) | 2006-03-15 | — | — | CN | disclosed |
| CN-1334798-A | Phenylglycine derivatives | HOFFMANN LA ROCHE (CH) | 2002-02-06 | — | — | CN | disclosed |