Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 19/20 | 0.71 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.71 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.71 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.52 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6634443 | 1.00 | CHRM3 (0.71) | CHRM3CHRM2CHRM1KEAP1NFE2L2 | |
| SCHEMBL6636379 | 0.87 | CHRM3 (0.71) | CHRM3CHRM2CHRM1 | |
| SCHEMBL27551652 | 0.87 | CHRM3 (0.71) | CHRM3CHRM2CHRM1 | |
| SCHEMBL6636685 | 0.85 | CHRM3 (0.74) | CHRM3CHRM2CHRM1 | |
| SCHEMBL27532998 | 0.85 | CHRM3 (0.74) | CHRM3CHRM2CHRM1 | |
| SCHEMBL6632334 | 0.84 | CHRM2 (0.77) | CHRM3CHRM2CHRM1 | |
| SCHEMBL28744180 | 0.84 | CHRM2 (0.77) | CHRM3CHRM2CHRM1 | |
| SCHEMBL15015222 | 0.83 | CHRM3 (0.76) | CHRM3CHRM2CHRM1KEAP1NFE2L2 | |
| SCHEMBL2444978 | 0.83 | CHRM3 (1.00) | CHRM3CHRM2CHRM1KEAP1NFE2L2 | |
| SCHEMBL2444975 | 0.83 | CHRM3 (1.00) | CHRM3CHRM2CHRM1KEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1290251-A | N-acyl cyclic amine derivatives | BANYU PHARMA CO LTD (JP) | 2001-04-04 | — | — | CN | claimed |
| CN-1290251-A | N-acyl cyclic amine derivatives | BANYU PHARMA CO LTD (JP) | 2001-04-04 | — | — | CN | disclosed |