Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VEGFA | P15692 | 1/20 | 0.48 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | TDO2 | P48775 | 1/20 | 0.44 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.44 |
| ▸ | TBK1 | Q9UHD2 | 6/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | GLS | O94925 | 2/20 | 0.42 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.41 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28449818 | 0.88 | VEGFA (0.49) | VEGFAEGLN1IDO1TDO2IDO2 | |
| SCHEMBL30038994 | 0.88 | VEGFA (0.49) | VEGFAEGLN1IDO1TDO2IDO2 | |
| SCHEMBL28659906 | 0.86 | KMT2A (0.49) | VEGFAEGLN1IDO1TDO2IDO2 | |
| SCHEMBL7238782 | 0.86 | IDO1 (0.48) | VEGFAEGLN1IDO1TDO2IDO2 | |
| SCHEMBL3731353 | 0.85 | VEGFA (0.53) | VEGFAEGLN1IDO1TDO2IDO2 | |
| SCHEMBL24507281 | 0.85 | IDO1 (0.49) | VEGFAEGLN1IDO1TDO2IDO2 | |
| SCHEMBL5481602 | 0.85 | VEGFA (0.52) | VEGFAEGLN1IDO1TDO2IDO2 | |
| SCHEMBL30560055 | 0.85 | IDO1 (0.49) | VEGFAEGLN1IDO1TDO2IDO2 | |
| SCHEMBL21198803 | 0.84 | VEGFA (0.55) | VEGFAEGLN1IDO1TDO2IDO2 | |
| SCHEMBL5470260 | 0.83 | VEGFA (0.50) | VEGFAEGLN1IDO1TDO2IDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1330657-C | Piperidine and piperazine derivatives | ASTRAZENECA AB (SE) | 2007-08-08 | — | — | CN | disclosed |