Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 18/20 | 0.60 |
| ▸ | CCNE1 | P24864 | 9/20 | 0.60 |
| ▸ | GSK3B | P49841 | 2/20 | 0.60 |
| ▸ | CCNA2 | P20248 | 7/20 | 0.57 |
| ▸ | CCNA1 | P78396 | 7/20 | 0.57 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.55 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.55 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.55 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.55 |
| ▸ | CDK1 | P06493 | 1/20 | 0.55 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.55 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.55 |
| ▸ | GLS | O94925 | 1/20 | 0.50 |
| ▸ | CDK9 | P50750 | 1/20 | 0.49 |
| ▸ | PDE5A | O76074 | 1/20 | 0.48 |
| ▸ | PDE1A | P54750 | 1/20 | 0.48 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.48 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5867802 | 0.89 | CDK2 (0.51) | CDK2CCNE1GSK3BCCNA2CCNA1 | |
| SCHEMBL5867894 | 0.86 | CDK2 (0.64) | CDK2CCNE1CCNA2CCNA1CDK5 | |
| SCHEMBL5867861 | 0.81 | CDK2 (0.70) | CDK2CCNE1CCNA2CCNA1CDK5 | |
| SCHEMBL5867440 | 0.80 | CDK2 (0.66) | CDK2CCNE1CCNA2CCNA1CDK5 | |
| SCHEMBL5867759 | 0.80 | CDK2 (0.51) | CDK2CCNE1GSK3BCCNA2CCNA1 | |
| SCHEMBL5867826 | 0.76 | CDK2 (0.50) | CDK2CCNE1GSK3BCCNA2CCNA1 | |
| SCHEMBL27564788 | 0.76 | CDK2 (0.53) | CDK2CCNE1GSK3BCCNA2CCNA1 | |
| SCHEMBL25334570 | 0.75 | CDK2 (0.66) | CDK2CCNE1GSK3BCCNA2CCNA1 | |
| SCHEMBL22312373 | 0.75 | CDK2 (1.00) | CDK2CCNE1GSK3B | |
| SCHEMBL22286843 | 0.75 | CCNE1 (1.00) | CDK2CCNE1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1454091-A | Immunostimulatory nucleic acids | UNIV IOWA RES FOUND (US) | 2003-11-05 | — | — | CN | disclosed |