Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 11/20 | 0.41 |
| ▸ | GPBAR1 | Q8TDU6 | 5/20 | 0.41 |
| ▸ | CYSLTR2 | Q9NS75 | 8/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27557793 | 0.97 | CYSLTR1 (0.40) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL4850041 | 0.91 | CYSLTR1 (0.41) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL4847070 | 0.89 | CYSLTR1 (0.39) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL7568755 | 0.87 | CYSLTR1 (0.41) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL4841568 | 0.84 | CYSLTR1 (0.43) | CYSLTR1CYSLTR2 | |
| SCHEMBL4848197 | 0.81 | CYSLTR1 (0.42) | CYSLTR1CYSLTR2 | |
| SCHEMBL27558048 | 0.80 | CYSLTR1 (0.39) | CYSLTR1GPBAR1CYSLTR2PDE10A | |
| SCHEMBL14021727 | 0.79 | CYSLTR1 (0.50) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL7568749 | 0.78 | CYSLTR1 (0.34) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL4848359 | 0.77 | CYSLTR1 (0.50) | CYSLTR1GPBAR1CYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101070316-A | Diaryl acid derivatives as PPAR receptor ligands | AVENTIS PHARMA GMBH (DE) | 2007-11-14 | — | — | CN | disclosed |
| CN-1331862-C | Diaryl acid derivatives as PPAR receptor ligands | AVENTIS PHARAMCEUTICALS PRODUC (DE) | 2007-08-15 | — | — | CN | disclosed |
| CN-1349525-A | Diaryl acid derivatives as PPAR receptor ligands | AVENTIS PHARAMCEUTICALS PRODUC (BE) | 2002-05-15 | — | — | CN | disclosed |