Chalcone

Chalcone

SCHEMBL27581

O=C(C=Cc1ccccc1)c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1B1 Q16678 10/20 1.00
MAPT P10636 6/20 1.00
MAOB P27338 6/20 1.00
LMNA P02545 2/20 1.00
BCHE P06276 2/20 1.00
TNFRSF1A P19438 2/20 1.00
PLIN1 O60240 1/20 1.00
ACHE P22303 1/20 1.00
RECQL P46063 1/20 1.00
PLIN5 Q00G26 1/20 1.00
ABHD5 Q8WTS1 1/20 1.00
CYP3A4 P08684 5/20 0.78
KMT2A Q03164 4/20 0.78
HSPD1 P10809 3/20 0.78
HSPE1 P61604 3/20 0.78
NFKB1 P19838 2/20 0.78
RAB9A P51151 2/20 0.78
NFKB2 Q00653 2/20 0.78
RELA Q04206 2/20 0.78
MEN1 O00255 2/20 0.78

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chalcone SCHEMBL454583 1.00 CYP1B1 (1.00) CYP1B1MAPTMAOBLMNABCHE
Chalcone SCHEMBL29922932 1.00 CYP1B1 (1.00) CYP1B1MAPTMAOBLMNABCHE
Chalcone SCHEMBL27580 1.00 CYP1B1 (1.00) CYP1B1MAPTMAOBLMNABCHE
Chalcone SCHEMBL28306720 1.00 CYP1B1 (1.00) CYP1B1MAPTMAOBLMNABCHE
Chalcone SCHEMBL29396001 1.00 CYP1B1 (1.00) CYP1B1MAPTMAOBLMNABCHE
Chalcone SCHEMBL2404758 1.00 CYP1B1 (1.00) CYP1B1MAPTMAOBLMNABCHE
Chalcone SCHEMBL2427445 0.98 CYP1B1 (0.96) CYP1B1MAPTMAOBLMNABCHE
Chalcone SCHEMBL527181 0.98 CYP1B1 (0.96) CYP1B1MAPTMAOBLMNABCHE
Chalcone SCHEMBL7861207 0.98 CYP1B1 (0.96) CYP1B1MAPTMAOBLMNABCHE
Chalcone SCHEMBL7653806 0.98 CYP1B1 (0.96) CYP1B1MAPTMAOBLMNABCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 35051 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3848462-B1 BAICALEIN- AND SCUTELLAREIN-SYNTHESIZING MICROORGANISM, PREPARATION METHOD, AND APPLICATIONS THEREOF CAS CENTER FOR EXCELLENCE IN MOLECULAR PLANT SCIENCES (CN) 2026-05-27 EP claimed
EP-4749337-A1 METHOD FOR PRODUCING CHOLESTERIC LIQUID CRYSTAL LAYER, CHOLESTERIC LIQUID CRYSTAL LAYER, REFLECTIVE FILM, LAMINATED GLASS, HEAD-UP DISPLAY SYSTEM, AND COMPOSITION FUJIFILM Corporation (JP) 2026-05-27 EP claimed
CN-121248445-B Naphthalene type chalcone compound and preparation method and application thereof BOZHOU UNIVERSITY (CN) 2026-05-26 CN claimed
CN-122059625-A Mineral wool binder 洛科威有限公司 2026-05-19 CN claimed
CN-122056936-A Application of chalcone in preparation of metabolism-related fatty liver disease intervention drugs 石家庄职业技术学院(石家庄开放大学) 2026-05-19 CN claimed
CN-122037460-A High adhesion epoxy resin composition and application thereof in semiconductor chip packaging 连云港昭华科技有限公司 2026-05-15 CN claimed
CN-122054895-A High-purity fluorine salt and preparation method and application thereof 中矿资源(天津)新材料有限公司 2026-05-15 CN claimed
US-12624214-B2 Polymerizable absorbers of UV and high energy visible light JOHNSON & JOHNSON VISION CARE, INC. (US) 2026-05-12 US claimed
CN-121518510-B Chalcone isopentenyl transferase gene GiPT, giPT protein, amplification primer set and application 中国中医科学院中药研究所 2026-05-12 CN claimed
CN-122011799-A Amphiphilic near-infrared two-region aza-fluoroborodipyrrole dye and preparation method thereof 天津大学 2026-05-12 CN claimed
US-4212998-A 1-Phenyl-3-(3-trifluoromethylphenyl)-2-propanol and process for its production HOOKER CHEMICALS & PLASTICS CORP. (US) 1980-07-15 US claimed
US-4191320-A THERMOPLASTIC RESIN, TWO AROMATIC CARBONYL SENSITIZERS OWENS-ILLINOIS, INC. (US) 1980-03-04 US claimed
US-4056665-A Composition and process OWENS-ILLINOIS, INC. (US) 1977-11-01 US claimed
US-4014896-A Catalytic dehydrogenation process for the preparation of 3,4,5-trisubstituted pyrazoles AMERICAN CYANAMID COMPANY (US) 1977-03-29 US claimed
US-3958991-A PHOTOCONDUCTOR EASTMAN KODAK COMPANY (US) 1976-05-25 US claimed
US-3956043-A LIGHT-SENSITIVE EPOXY COMPOUNDS CIBA-GEIGY CORPORATION (US) 1976-05-11 US claimed
US-3951884-A STYRENE OR METHYL METHACRYLATE-DIENE-UNSATURATED KETONE SEKISUI KAGAKU KOGYO KABUSHIKI KAISHA (JA) 1976-04-20 US claimed
US-3947405-A Process for making neohesperidine dihydrochalcone GIVAUDAN CORPORATION (US) 1976-03-30 US claimed
US-3938994-A Pyrylium dyes for electrophotographic composition and element EASTMAN KODAK COMPANY (US) 1976-02-17 US claimed
US-3931152-A ANTITUBERCULAR AMERICAN CYANAMID COMPANY (US) 1976-01-06 US claimed