Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 16/20 | 0.72 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.49 |
| ▸ | KIT | P10721 | 1/20 | 0.45 |
| ▸ | FLT3 | P36888 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27584791 | 0.88 | KDR (0.78) | KDRCHEK1KITFLT3SRC | |
| SCHEMBL7229090 | 0.87 | KDR (0.75) | KDRCHEK1KITFLT3SRC | |
| SCHEMBL6177379 | 0.84 | KDR (1.00) | KDRCHEK1 | |
| SCHEMBL14022595 | 0.83 | KDR (0.98) | KDRCHEK1 | |
| SCHEMBL7237800 | 0.83 | KDR (0.98) | KDRCHEK1 | |
| SCHEMBL6180735 | 0.83 | KDR (1.00) | KDRCHEK1 | |
| SCHEMBL6179608 | 0.83 | KDR (1.00) | KDRCHEK1SRC | |
| SCHEMBL7236764 | 0.83 | KDR (0.86) | KDRCHEK1SRC | |
| SCHEMBL27584790 | 0.82 | KDR (0.67) | KDRCHEK1KITFLT3SRC | |
| SCHEMBL7234536 | 0.82 | KDR (0.79) | KDRCHEK1KITFLT3SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1390215-A | Tyrosine kinase inhibitors | MERCK & CO INC (US) | 2003-01-08 | — | — | CN | claimed |
| CN-1390215-A | Tyrosine kinase inhibitors | MERCK & CO INC (US) | 2003-01-08 | — | — | CN | disclosed |