SCHEMBL27587355

SCHEMBL27587355

CCCCc1ccc(CNc2ncnc3nc[nH]c23)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.73
KMT2A Q03164 3/20 0.73
MAPT P10636 3/20 0.73
NPC1 O15118 2/20 0.73
RAB9A P51151 2/20 0.73
HPGD P15428 1/20 0.73
PRMT1 Q99873 1/20 0.72
LMNA P02545 7/20 0.67
TSHR P16473 7/20 0.67
MAPK1 P28482 2/20 0.67
CYP1A2 P05177 2/20 0.67
CYP2D6 P10635 1/20 0.67
CDK2 P24941 1/20 0.67
HSD17B10 Q99714 5/20 0.62
HTT P42858 5/20 0.60
SMN1; SMN2 Q16637 6/20 0.58
L3MBTL1 Q9Y468 1/20 0.58
TAAR1 Q96RJ0 1/20 0.57
KDR P35968 2/20 0.56
CDC7 O00311 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4930421 0.97 PRMT1 (0.72) MEN1KMT2AMAPTNPC1RAB9A
SCHEMBL4917765 0.96 PRMT1 (0.70) MEN1KMT2AMAPTNPC1RAB9A
SCHEMBL4933979 0.96 PRMT1 (0.70) MEN1KMT2AMAPTNPC1RAB9A
SCHEMBL4922873 0.92 PRMT1 (0.76) MEN1KMT2AMAPTNPC1RAB9A
SCHEMBL4922895 0.88 PRMT1 (0.69) MEN1KMT2AMAPTNPC1RAB9A
SCHEMBL4920962 0.87 PRMT1 (0.80) MEN1KMT2AMAPTNPC1RAB9A
SCHEMBL4937110 0.85 PRMT1 (0.66) MEN1KMT2AMAPTNPC1RAB9A
SCHEMBL4921039 0.84 PRMT1 (0.65) MEN1KMT2AMAPTNPC1RAB9A
SCHEMBL4921306 0.84 PRMT1 (0.65) MEN1KMT2AMAPTNPC1RAB9A
SCHEMBL723526 0.84 PRMT1 (1.00) MEN1KMT2ANPC1RAB9APRMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1556808-A Based on N6Heterocyclic compounds of substituted adenine, process for their preparation, their use for the preparation of medicaments, cosmetic preparations and growth regulators, pharmaceutical preparations, cosmetic preparations and growth regulators containing these compounds �ݿ˹��͹���������ʵ��ֲ��ѧ�� 2004-12-22 CN claimed
CN-1556808-A Based on N6Heterocyclic compounds of substituted adenine, process for their preparation, their use for the preparation of medicaments, cosmetic preparations and growth regulators, pharmaceutical preparations, cosmetic preparations and growth regulators containing these compounds �ݿ˹��͹���������ʵ��ֲ��ѧ�� 2004-12-22 CN disclosed