Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.39 |
| ▸ | PDE4A | P27815 | 2/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19015182 | 0.85 | HPGD (0.44) | HPGDRECQLDPP4MEN1ALDH1A1 | |
| SCHEMBL29206701 | 0.80 | HPGD (0.49) | HPGDRECQLDPP4MEN1ALDH1A1 | |
| SCHEMBL20970529 | 0.80 | HPGD (0.49) | HPGDRECQLDPP4MEN1ALDH1A1 | |
| SCHEMBL29214583 | 0.80 | HPGD (0.49) | HPGDRECQLDPP4MEN1ALDH1A1 | |
| SCHEMBL19015480 | 0.80 | HPGD (0.49) | HPGDRECQLDPP4MEN1ALDH1A1 | |
| SCHEMBL23579480 | 0.80 | HPGD (0.49) | HPGDRECQLDPP4MEN1ALDH1A1 | |
| SCHEMBL15740593 | 0.80 | HPGD (0.49) | HPGDRECQLDPP4MEN1ALDH1A1 | |
| SCHEMBL16374503 | 0.80 | HPGD (0.49) | HPGDRECQLDPP4MEN1ALDH1A1 | |
| SCHEMBL15742958 | 0.80 | HPGD (0.49) | HPGDRECQLDPP4MEN1ALDH1A1 | |
| SCHEMBL27491784 | 0.79 | PDE4D (0.51) | HPGDRECQLDPP4MAPTPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1391473-A | VLA-4 inhibitor compounds | DAIICHI SEIYAKU CO (JP) | 2003-01-15 | — | — | CN | disclosed |