Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 7/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19329647 | 0.76 | CYP19A1 (0.41) | CYP19A1ALDH1A1KDM4EMEN1LMNA | |
| SCHEMBL1878657 | 0.75 | CYP19A1 (0.55) | CYP19A1ALDH1A1TSHRKDM4EGAA | |
| SCHEMBL12260330 | 0.74 | CYP19A1 (0.51) | CYP19A1ALDH1A1TSHRKDM4EPLA2G10 | |
| SCHEMBL10208758 | 0.74 | CYP19A1 (0.57) | CYP19A1ALDH1A1TSHRKDM4EPLA2G10 | |
| SCHEMBL28236106 | 0.74 | TSHR (0.54) | CYP19A1ALDH1A1TSHRKDM4EPLA2G10 | |
| SCHEMBL13622538 | 0.72 | CYP19A1 (0.47) | CYP19A1ALDH1A1TSHRKDM4EKMT2A | |
| SCHEMBL12260367 | 0.72 | CYP19A1 (0.41) | CYP19A1ALDH1A1TSHRPLA2G10 | |
| SCHEMBL11377192 | 0.71 | CYP19A1 (0.51) | CYP19A1ALDH1A1TSHRKDM4EMEN1 | |
| SCHEMBL19219061 | 0.71 | AOC3 (0.54) | CYP19A1ALDH1A1TSHRKDM4EKMT2A | |
| SCHEMBL28345828 | 0.70 | CYP19A1 (0.50) | CYP19A1ALDH1A1TSHRKDM4EPLA2G10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100338074-C | Heterocyclic compounds and cerebral function improvers containing same as active | ZENYAKU KOGYO KK (JP) | 2007-09-19 | — | — | CN | disclosed |
| CN-1531540-A | Heterocyclic compounds and cerebral function improvers containing same as active | ������ҩ��ҵ��ʽ���� | 2004-09-22 | — | — | CN | disclosed |