Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 15/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 13/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6440596 | 0.88 | KDM4E (0.42) | ADORA1ADORA2AADORA2BMAPTKDM4E | |
| SCHEMBL6442849 | 0.85 | ADORA1 (0.37) | ADORA1ADORA2AADORA2BMAPTRXFP1 | |
| SCHEMBL6440737 | 0.84 | ADORA1 (0.36) | ADORA1ADORA2AADORA2BMAPTKDM4E | |
| SCHEMBL6444418 | 0.82 | ADORA1 (0.36) | ADORA1ADORA2AADORA2BMAPTKDM4E | |
| SCHEMBL6444885 | 0.78 | ADORA2A (0.61) | ADORA1ADORA2AADORA2BMAPTKDM4E | |
| SCHEMBL6442282 | 0.78 | MAPT (0.57) | ADORA1ADORA2AADORA2BMAPTRXFP1 | |
| SCHEMBL6441010 | 0.76 | GRM4 (0.40) | ADORA1ADORA2AADORA2BMAPTKDM4E | |
| SCHEMBL6440809 | 0.76 | ADORA2A (0.66) | ADORA1ADORA2AADORA2BMAPTKDM4E | |
| SCHEMBL6442913 | 0.74 | ADORA1 (0.36) | ADORA1ADORA2AADORA2BKDM4E | |
| SCHEMBL6441176 | 0.74 | ADORA1 (0.36) | ADORA1ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1438890-A | Adenosine receptor modulators | HOFFMANNLA ROCHE AG F (CH) | 2003-08-27 | — | — | CN | disclosed |