Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | TLR4 | O00206 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27576686 | 0.89 | TLR4 (0.57) | TSHRKDM4EALDH1A1TLR4HSD17B10 | |
| SCHEMBL871405 | 0.87 | TLR4 (0.62) | TSHRKDM4EALDH1A1TLR4HSD17B10 | |
| SCHEMBL872228 | 0.82 | TLR4 (0.64) | TSHRKDM4EALDH1A1TLR4HSD17B10 | |
| SCHEMBL27592263 | 0.81 | TLR4 (0.48) | TSHRKDM4EALDH1A1TLR4KMT2A | |
| SCHEMBL6053601 | 0.81 | TLR4 (0.52) | TSHRKDM4ETLR4SMN1; SMN2MRGPRX1 | |
| SCHEMBL27573690 | 0.81 | TLR4 (0.52) | TSHRALDH1A1TLR4MEN1GAA | |
| SCHEMBL27573738 | 0.80 | HPGD (0.47) | TSHRALDH1A1TLR4HPGDMEN1 | |
| SCHEMBL27883083 | 0.79 | TLR4 (0.41) | KDM4EALDH1A1TLR4HPGDSMN1; SMN2 | |
| SCHEMBL27592264 | 0.78 | TLR4 (0.60) | TSHRKDM4EALDH1A1TLR4HSD17B10 | |
| SCHEMBL28159696 | 0.77 | TLR4 (0.48) | TSHRALDH1A1TLR4NPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102821763-B | Compound for inhibiting peripheral nerve disorder induced by anticancer agent | 武田药品工业株式会社 | 2017-09-22 | — | — | CN | disclosed |
| CN-101212986-B | Stable emulsified composition | TAKEDA PHARMACEUTICAL | 2015-01-14 | — | — | CN | disclosed |
| CN-102821763-A | Compound for inhibiting peripheral nerve disorder induced by anticancer agent | TAKEDA PHARMACEUTICAL | 2012-12-12 | — | — | CN | disclosed |
| CN-102670503-A | Stable emulsion composition | TAKEDA PHARMACEUTICAL | 2012-09-19 | — | — | CN | disclosed |
| CN-1416341-B | Stable emulsion compositions | TAKEDA CHEMICAL INDUSTRIES LTD | 2010-05-05 | — | — | CN | disclosed |
| CN-101212986-A | stable emulsified composition | TAKEDA PHARMACEUTICAL (JP) | 2008-07-02 | — | — | CN | disclosed |
| CN-1416341-A | Stable emulsion compsns | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-05-07 | — | — | CN | disclosed |