Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 8/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PYGL | P06737 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.37 |
| ▸ | ACLY | P53396 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL872269 | 0.97 | TLR4 (0.73) | TLR4KMT2ANPC1RAB9AHPGD | |
| SCHEMBL3690868 | 0.97 | TLR4 (0.73) | TLR4KMT2ANPC1RAB9AHPGD | |
| SCHEMBL722368 | 0.97 | TLR4 (0.73) | TLR4KMT2ANPC1RAB9AHPGD | |
| SCHEMBL27592449 | 0.92 | TLR4 (0.72) | TLR4KMT2ANPC1RAB9AHPGD | |
| SCHEMBL28159349 | 0.85 | TLR4 (0.58) | TLR4NPC1RAB9AMRGPRX1ACLY | |
| SCHEMBL6229405 | 0.85 | TLR4 (0.58) | TLR4KMT2ANPC1RAB9AHPGD | |
| SCHEMBL872918 | 0.85 | TLR4 (0.58) | TLR4NPC1RAB9AMRGPRX1ACLY | |
| SCHEMBL16950256 | 0.85 | TLR4 (0.66) | TLR4KMT2ANPC1RAB9AMAPT | |
| SCHEMBL871253 | 0.85 | TLR4 (1.00) | TLR4KMT2AMRGPRX1LMNA | |
| SCHEMBL6053336 | 0.83 | TLR4 (0.61) | TLR4KMT2ANPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102670503-A | Stable emulsion composition | TAKEDA PHARMACEUTICAL | 2012-09-19 | — | — | CN | disclosed |
| CN-1416341-B | Stable emulsion compositions | TAKEDA CHEMICAL INDUSTRIES LTD | 2010-05-05 | — | — | CN | disclosed |
| CN-101212986-A | stable emulsified composition | TAKEDA PHARMACEUTICAL (JP) | 2008-07-02 | — | — | CN | disclosed |
| CN-1416341-A | Stable emulsion compsns | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-05-07 | — | — | CN | disclosed |