Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | POLM | Q9NP87 | 2/20 | 0.41 |
| ▸ | POLK | Q9UBT6 | 2/20 | 0.41 |
| ▸ | POLL | Q9UGP5 | 2/20 | 0.41 |
| ▸ | POLH | Q9Y253 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.40 |
| ▸ | NOX1 | Q9Y5S8 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28776094 | 0.93 | GAA (0.43) | MEN1KMT2AKDM4ERECQLGAA | |
| SCHEMBL27595098 | 0.88 | MAPK1 (0.40) | MEN1KMT2AKDM4ERECQLGAA | |
| SCHEMBL27595216 | 0.87 | GAA (0.45) | MEN1KMT2AKDM4EGAAMAPT | |
| SCHEMBL27595100 | 0.86 | HPGD (0.49) | MEN1KMT2AGAAMAPTHPGD | |
| SCHEMBL27326368 | 0.82 | NOX1 (0.42) | MEN1KMT2AKDM4EGAAMAPT | |
| SCHEMBL31087634 | 0.80 | NOX1 (0.48) | MEN1KMT2AKDM4EGAAMAPT | |
| SCHEMBL28656212 | 0.78 | NOX1 (0.46) | MEN1KMT2AGAAMAPTALOX15 | |
| SCHEMBL16756230 | 0.75 | KDM4E (0.75) | MEN1KMT2AKDM4ERECQLPOLM | |
| SCHEMBL9483128 | 0.74 | NOX1 (0.42) | MEN1KMT2AKDM4EGAAMAPT | |
| SCHEMBL105775 | 0.72 | NOX1 (0.53) | MEN1KMT2AGAAMAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100558365-C | Conjugated antipsychotics and uses thereof | TEL AVIA UNIVERSITY LTD (IL) | 2009-11-11 | — | — | CN | disclosed |
| CN-101445494-A | Conjugated psychotropic drugs and uses thereof | UNIV RAMOT (IL) | 2009-06-03 | — | — | CN | disclosed |
| CN-1596141-A | Conjugated antipsychotics and uses thereof | RAMOT AT TEL AVIA UNIVERSITY L (IL) | 2005-03-16 | — | — | CN | disclosed |