Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27595154 | 0.91 | KDM4E (0.42) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL27577003 | 0.84 | CCNE1 (0.33) | HDAC6HSP90AA1HSP90AB1 | |
| SCHEMBL2911493 | 0.79 | HDAC6 (0.43) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL2911483 | 0.79 | HDAC6 (0.43) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL27577011 | 0.77 | ADORA2A (0.44) | ALDH1A1 | |
| SCHEMBL27577000 | 0.77 | ADORA2A (0.44) | ALDH1A1 | |
| SCHEMBL4278186 | 0.77 | CCNE1 (0.34) | ALDH1A1HDAC6HSP90AA1HSP90AB1 | |
| SCHEMBL14138147 | 0.72 | HDAC6 (0.46) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL3290197 | 0.71 | KDM4E (0.41) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL4270191 | 0.70 | KDM4E (0.40) | KDM4EALDH1A1HPGDADRA1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100347185-C | Novel acyclic nucleoside phosphonate derivatives, salts thereof and process for the preparation of the same | LG LIFE SCIENCE CO LTD (KR) | 2007-11-07 | — | — | CN | disclosed |
| CN-1487949-A | Novel acyclic nucleoside phosphonate derivatives, salts thereof and process for the preparation of the same | ��ʽ����LG������ѧ | 2004-04-07 | — | — | CN | disclosed |