Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 15/20 | 0.54 |
| ▸ | LTA4H | P09960 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27596423 | 0.91 | LSS (0.48) | LSSMEN1KMT2A | |
| SCHEMBL27578412 | 0.89 | LSS (0.48) | LSSMEN1KMT2A | |
| SCHEMBL28749500 | 0.88 | LSS (0.47) | LSSMEN1KMT2A | |
| SCHEMBL4802756 | 0.86 | LSS (0.50) | LSSMEN1KMT2A | |
| SCHEMBL4799256 | 0.82 | LSS (0.61) | LSSLTA4HMEN1KMT2A | |
| SCHEMBL4799266 | 0.82 | LSS (0.61) | LSSLTA4HMEN1KMT2A | |
| SCHEMBL4804262 | 0.79 | LSS (0.64) | LSSMEN1KMT2A | |
| SCHEMBL4804515 | 0.79 | LSS (0.64) | LSSMEN1KMT2A | |
| SCHEMBL4804268 | 0.79 | LSS (0.64) | LSSMEN1KMT2A | |
| SCHEMBL4810164 | 0.79 | LSS (0.64) | LSSMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100455566-C | Novel derivatives of aminocyclohexane | HOFFMANN LA ROCHE (CH) | 2009-01-28 | — | — | CN | disclosed |
| CN-1468214-A | Novel derivatives of aminocyclohexane | - | 2004-01-14 | — | — | CN | disclosed |