Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.62 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PNMT | P11086 | 2/20 | 0.36 |
| ▸ | F10 | P00742 | 2/20 | 0.34 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.32 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.32 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6165065 | 0.81 | DPP4 (0.62) | DPP4NOS3NOS1NOS2ADRA2C | |
| SCHEMBL2981250 | 0.78 | DPP4 (0.91) | DPP4NOS3NOS1NOS2KMT2A | |
| SCHEMBL469051 | 0.78 | DPP4 (1.00) | DPP4KMT2APNMTHTR7FOLH1 | |
| SCHEMBL29872374 | 0.78 | DPP4 (1.00) | DPP4KMT2APNMTHTR7FOLH1 | |
| SCHEMBL3789431 | 0.76 | DPP4 (0.72) | DPP4NOS3NOS1NOS2PNMT | |
| SCHEMBL399409 | 0.76 | DPP4 (0.72) | DPP4NOS3NOS1NOS2CYP2C19 | |
| Hydrochloric Acid SCHEMBL4776720 | 0.76 | DPP4 (0.95) | DPP4NOS3NOS1NOS2KMT2A | |
| SCHEMBL27689661 | 0.76 | DPP4 (0.64) | DPP4NOS3NOS1NOS2CYP2C19 | |
| SCHEMBL7142529 | 0.75 | DPP4 (0.69) | DPP4NOS3NOS1NOS2CYP2C19 | |
| SCHEMBL3723618 | 0.75 | DPP4 (0.69) | DPP4NOS3NOS1NOS2PNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1481377-A | Cyclic beta-amino acid derivatives as inhibitors of matrix metalloproteinases and TNF-alpha | ����˹�ж�-����˹˹����ҩƷ��˾ | 2004-03-10 | — | — | CN | disclosed |