Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CDC25B | P30305 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27598994 | 0.86 | ACP3 (0.43) | ACP3TSHRCYP2A6CYP1A2KMT2A | |
| SCHEMBL27617481 | 0.78 | TSHR (0.47) | ACP3TSHRCYP2A6CYP1A2KMT2A | |
| SCHEMBL12984308 | 0.74 | ACP3 (0.39) | ACP3TSHRCYP2A6CYP1A2KMT2A | |
| SCHEMBL13465324 | 0.73 | AKR1B1 (0.51) | ACP3TSHRCYP2A6CYP1A2KMT2A | |
| SCHEMBL27617500 | 0.73 | NPC1 (0.52) | KMT2AMEN1L3MBTL1NCEH1ALDH1A1 | |
| SCHEMBL10634101 | 0.73 | TSHR (0.48) | ACP3TSHRCYP2A6CYP1A2MAPK1 | |
| SCHEMBL28143904 | 0.72 | TSHR (0.44) | ACP3TSHRCYP2A6CYP1A2KMT2A | |
| Hydrogen Peroxide SCHEMBL8610674 | 0.72 | CYP1A2 (0.52) | ACP3TSHRCYP2A6CYP1A2KMT2A | |
| SCHEMBL18242403 | 0.72 | CYP1A2 (0.52) | ACP3TSHRCYP2A6CYP1A2KMT2A | |
| SCHEMBL2126761 | 0.71 | CYP1A2 (0.56) | ACP3TSHRCYP2A6CYP1A2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1633291-A | 2-oxazolamines and their use as 5-HT2BUse of receptor antagonists | PHARMAGENE LAB LTD (GB) | 2005-06-29 | — | — | CN | disclosed |