Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | MPL | P40238 | 1/20 | 0.43 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.42 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | PRKACA | P17612 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | FRK | P42685 | 1/20 | 0.42 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.42 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.42 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.42 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1445089 | 0.85 | MAPK14 (0.44) | IDO1MPLDCLK1PRKD3MAP4K4 | |
| SCHEMBL27771733 | 0.83 | MAP4K4 (0.47) | DCLK1PRKD3MAP4K4EGFRPRKACA | |
| SCHEMBL28101879 | 0.82 | IDO1 (0.49) | IDO1DCLK1PRKD3MAP4K4EGFR | |
| SCHEMBL30082281 | 0.82 | MAPK10 (0.40) | DCLK1PRKD3MAP4K4EGFRPRKACA | |
| SCHEMBL29050794 | 0.82 | MAPK14 (0.40) | DCLK1PRKD3MAP4K4EGFRPRKACA | |
| SCHEMBL30052825 | 0.82 | MAPK14 (0.40) | DCLK1PRKD3MAP4K4EGFRPRKACA | |
| Pyrazine SCHEMBL28285882 | 0.81 | MAPK14 (0.43) | IDO1MPLDCLK1PRKD3MAP4K4 | |
| SCHEMBL27786704 | 0.81 | MAPK14 (0.43) | IDO1DCLK1PRKD3MAP4K4EGFR | |
| SCHEMBL10601314 | 0.78 | MAPK9 (0.43) | DCLK1PRKD3MAP4K4EGFRPRKACA | |
| SCHEMBL28331391 | 0.77 | GRM5 (0.62) | IDO1MAPK14GRM5P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106035343-A | Insecticidal triazines and pyrimidines | 韦斯塔隆公司 | 2016-10-26 | — | — | CN | disclosed |
| CN-100415725-C | Pyrimidine compound and application thereof | SUMITOMO CHEMICAL CO (JP) | 2008-09-03 | — | — | CN | disclosed |
| CN-1478082-A | Pyrimidine compound and application thereof | ס�ѻ�ѧ��ҵ��ʽ���� | 2004-02-25 | — | — | CN | disclosed |