⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14914212 | 0.74 | HMGCR (0.40) | — | |
| SCHEMBL818454 | 0.74 | HMGCR (0.40) | — | |
| SCHEMBL27205974 | 0.74 | TSHR (0.31) | — | |
| SCHEMBL1032054 | 0.73 | — | — | |
| SCHEMBL10702393 | 0.73 | — | — | |
| T-Butylacetic Acid SCHEMBL10950588 | 0.71 | HMGCR (0.61) | — | |
| SCHEMBL104505 | 0.71 | — | — | |
| T-Butylacetic Acid SCHEMBL71379 | 0.71 | — | — | |
| SCHEMBL18799389 | 0.71 | — | — | |
| SCHEMBL14879687 | 0.71 | TSHR (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 763 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114014878-B | Conjugated alkenyl zinc reagent, preparation method and application thereof | 南开大学 | 2024-06-07 | — | — | CN | claimed |
| CN-116535439-B | Cyclopropane skeleton monophosphine ligand and palladium complex thereof, and preparation method and application thereof | 南开大学 | 2024-05-28 | — | — | CN | claimed |
| CN-116535439-A | Cyclopropane skeleton monophosphine ligand and palladium complex thereof, and preparation method and application thereof | 南开大学 | 2023-08-04 | — | — | CN | claimed |
| WO-2023142725-A1 | CYCLOPROPANE SKELETON MONOPHOSPHINE LIGAND AND PALLADIUM COMPLEX THEREOF AS WELL AS PREPARATION METHOD AND USE THEREOF | 南开大学 | 2023-08-03 | — | — | WO | claimed |
| CN-116003462-A | Silicon-based substituted chiral amine and preparation method and application thereof | 南开大学 | 2023-04-25 | — | — | CN | claimed |
| CN-115850328-A | Diphosphine ligand with cyclopropane skeleton and cobalt complex thereof, preparation method and application | 南开大学 | 2023-03-28 | — | — | CN | claimed |
| CN-114249725-A | Preparation method and application of 2-imine-9-aryl substituted phenanthroline and iron complex thereof | 南开大学 | 2022-03-29 | — | — | CN | claimed |
| CN-114014878-A | Novel conjugated alkenyl zinc reagent, preparation method and application thereof | 南开大学 | 2022-02-08 | — | — | CN | claimed |
| CN-106518931-B | Novel iridium complex of spiro phosphine-carboxylic acid and preparation method and application thereof | 南开大学 | 2021-08-24 | — | — | CN | claimed |
| US-20200390100-A1 | SUBSTITUTED N-HETEROCYCLYL- AND N-HETEROARYL-TETRAHYDROPYRIMIDINONES AND THE SALTS THEREOF, AND THE USE OF SAME AS HERBICIDAL ACTIVE SUBSTANCES | BAYER AG (DE) | 2020-12-17 | — | — | US | claimed |
| EP-1045841-B1 | NOVEL GENIPIN DERIVATIVE HAVING LIVER PROTECTION ACTIVITY | CHOONGWAE PHARMA CORP (KR) | 2002-12-04 | — | — | EP | claimed |
| US-6262083-B1 | Genipin derivative having liver protection activity | CHOONGWAE PHARMA CORPORATION (KR) | 2001-07-17 | — | — | US | claimed |
| EP-1045841-A1 | NOVEL GENIPIN DERIVATIVE HAVING LIVER PROTECTION ACTIVITY | Choongwae Pharma Corporation (KR) | 2000-10-25 | — | — | EP | claimed |
| WO-1999023090-A1 | NOVEL GENIPIN DERIVATIVE HAVING LIVER PROTECTION ACTIVITY | CHOONGWAE PHARMA CORPORATION (KR) | 1999-05-14 | — | — | WO | claimed |
| EP-0019411-B1 | 1-PHENYL-2-AMINOETHANOL DERIVATIVES, PROCESSES FOR THEIR MANUFACTURE AND PHARMACEUTICAL COMPOSITIONS THEREOF | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-12-22 | — | — | EP | claimed |
| US-4323575-A | TOPICAL ANTIINFLAMMATORY AGENTS | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1982-04-06 | — | — | US | claimed |
| EP-0006298-B1 | ANTI-INFLAMMATORY 1-PHENYL-2-AMINOETHANOL DERIVATIVES, PHARMACEUTICAL COMPOSITIONS THEREOF FOR TOPICAL USE, AND PROCESSES FOR THEIR MANUFACTURE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-03-31 | — | — | EP | claimed |
| US-4303649-A | ANTIINFLAMMATORY AGENTS | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1981-12-01 | — | — | US | claimed |
| EP-0019411-A1 | 1-Phenyl-2-aminoethanol derivatives, processes for their manufacture and pharmaceutical compositions thereof | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1980-11-26 | — | — | EP | claimed |
| EP-0006298-A1 | Anti-inflammatory 1-phenyl-2-aminoethanol derivatives, pharmaceutical compositions thereof for topical use, and processes for their manufacture | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1980-01-09 | — | — | EP | claimed |