Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.80 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.78 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.78 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.78 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL557559 | 0.93 | DPP4 (0.78) | DPP4CHRM1CHRM2CHRM3KCNH2 | |
| SCHEMBL27583114 | 0.93 | DPP4 (0.77) | DPP4CHRM1CHRM2CHRM3KCNH2 | |
| SCHEMBL557042 | 0.91 | DPP4 (0.81) | DPP4CHRM1CHRM2CHRM3KCNH2 | |
| SCHEMBL556292 | 0.90 | DPP4 (0.82) | DPP4CHRM1CHRM2CHRM3KCNH2 | |
| SCHEMBL27583063 | 0.90 | DPP4 (0.81) | DPP4CHRM1CHRM2CHRM3KCNH2 | |
| SCHEMBL555496 | 0.90 | DPP4 (0.85) | DPP4CHRM1CHRM2CHRM3KCNH2 | |
| SCHEMBL557066 | 0.89 | DPP4 (0.78) | DPP4CHRM1CHRM2CHRM3KCNH2 | |
| SCHEMBL556429 | 0.89 | DPP4 (0.80) | DPP4CHRM1CHRM2CHRM3KCNH2 | |
| Hydrochloric Acid SCHEMBL637347 | 0.89 | DPP4 (0.84) | DPP4CHRM1CHRM2CHRM3KCNH2 | |
| SCHEMBL636660 | 0.89 | DPP4 (1.00) | DPP4CHRM1CHRM2CHRM3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101293888-B | Xanthine derivative, production and use thereof as a medicament | BOEHRINGER INGELHEIM PHARMA | 2013-09-25 | — | — | CN | disclosed |
| CN-101293888-A | Xanthine derivative, production and use thereof as a medicament | BOEHRINGER INGELHEIM PHARMA (DE) | 2008-10-29 | — | — | CN | disclosed |
| CN-100408579-C | Xanthine derivatives, process for their preparation and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA (DE) | 2008-08-06 | — | — | CN | disclosed |
| CN-1492870-A | Xanthine derivatives, process for their preparation and their use as pharmaceutical compositions | ���ָ��Ӣ��ķ�������Ϲ�˾ | 2004-04-28 | — | — | CN | disclosed |