Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CFTR | P13569 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | LMNA | P02545 | 7/20 | 0.43 |
| ▸ | RAB9A | P51151 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.43 |
| ▸ | RELA | Q04206 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30031302 | 0.76 | HDAC3 (0.56) | KMT2AMEN1HTTMAPTRAB9A | |
| SCHEMBL26967631 | 0.76 | HDAC3 (0.56) | KMT2AMEN1HTTMAPTRAB9A | |
| SCHEMBL22305996 | 0.74 | HDAC3 (0.60) | KMT2AMEN1HTTMAPTLMNA | |
| SCHEMBL25193417 | 0.72 | HDAC3 (0.58) | KMT2AMEN1HTTMAPTRAB9A | |
| SCHEMBL21241785 | 0.72 | HDAC3 (0.58) | KMT2AMEN1HTTMAPTRAB9A | |
| SCHEMBL30061335 | 0.72 | HDAC3 (0.58) | KMT2AMEN1HTTMAPTRAB9A | |
| SCHEMBL21224263 | 0.71 | HDAC3 (0.60) | KMT2AMEN1HTTMAPTRAB9A | |
| SCHEMBL22306000 | 0.71 | HDAC3 (0.58) | KMT2AMEN1HTTMAPTRAB9A | |
| SCHEMBL30058922 | 0.71 | HDAC3 (0.60) | KMT2AMEN1HTTMAPTRAB9A | |
| SCHEMBL31084669 | 0.71 | HDAC3 (0.58) | KMT2AMEN1HTTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1473157-A | Amide derivatives | ֮����ҩ��ʽ���� | 2004-02-04 | — | — | CN | disclosed |