Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21279500 | 0.95 | HCRTR2 (0.37) | HCRTR2HCRTR1 | |
| SCHEMBL2737650 | 0.92 | HCRTR1 (0.37) | HCRTR2HCRTR1 | |
| SCHEMBL2738165 | 0.92 | HCRTR2 (0.37) | HCRTR2HCRTR1 | |
| SCHEMBL19447411 | 0.92 | HCRTR1 (0.39) | HCRTR2HCRTR1 | |
| SCHEMBL15316970 | 0.91 | HCRTR2 (0.37) | HCRTR2HCRTR1 | |
| SCHEMBL2738167 | 0.91 | HCRTR2 (0.37) | HCRTR2HCRTR1 | |
| SCHEMBL21279839 | 0.91 | DHODH (0.39) | HCRTR2HCRTR1 | |
| SCHEMBL21279831 | 0.91 | DHODH (0.39) | HCRTR2HCRTR1 | |
| SCHEMBL19447674 | 0.90 | HCRTR1 (0.36) | HCRTR2HCRTR1 | |
| SCHEMBL2737600 | 0.89 | HCRTR1 (0.37) | HCRTR2HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120003215-A1 | PYRAZOLO[1,5-A]PYRIMIDINES FOR ANTIVIRAL TREATMENT | GILEAD SCIENCES, INC. (US) | 2012-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120003215-A1 | PYRAZOLO[1,5-A]PYRIMIDINES FOR ANTIVIRAL TREATMENT | TYMP, ZC3HAV1, TYMS | HCRTR2 4720/4885HCRTR1 4492/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.