Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 14/20 | 0.61 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | MMP9 | P14780 | 2/20 | 0.40 |
| ▸ | MMP8 | P22894 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27605905 | 0.88 | F10 (0.74) | F10RORCKDR | |
| SCHEMBL3862516 | 0.82 | F10 (0.88) | F10KDM4ESMN1; SMN2KDRMEN1 | |
| SCHEMBL3868033 | 0.76 | F10 (0.71) | F10 | |
| SCHEMBL3861744 | 0.74 | F10 (0.47) | F10KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL3872612 | 0.73 | F10 (0.59) | F10 | |
| SCHEMBL3866715 | 0.71 | F10 (0.88) | F10 | |
| SCHEMBL3866098 | 0.71 | F10 (0.88) | F10 | |
| SCHEMBL3861343 | 0.71 | F10 (0.74) | F10 | |
| SCHEMBL3868937 | 0.71 | F10 (0.74) | F10 | |
| SCHEMBL3871409 | 0.70 | F10 (0.71) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1674893-A | Benzimidazole derivatives | MERCK PATENT GMBH (DE) | 2005-09-28 | — | — | CN | claimed |
| CN-1674893-A | Benzimidazole derivatives | MERCK PATENT GMBH (DE) | 2005-09-28 | — | — | CN | disclosed |