⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9309154 | 0.97 | — | — | |
| SCHEMBL3150466 | 0.63 | — | — | |
| SCHEMBL17675345 | 0.62 | — | — | |
| SCHEMBL1568070 | 0.62 | — | — | |
| SCHEMBL9364529 | 0.62 | — | — | |
| SCHEMBL2874183 | 0.62 | — | — | |
| SCHEMBL3903837 | 0.61 | IDO1 (0.44) | — | |
| SCHEMBL9218615 | 0.60 | — | — | |
| SCHEMBL473200 | 0.60 | — | — | |
| SCHEMBL292044 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 432 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4504712-A1 | GPR35 MODULATORS AND USES THEREOF | Crossignal Therapeutics, Inc. (US) | 2025-02-12 | — | — | EP | claimed |
| CN-119137105-A | GPR35 modulators and uses thereof | 交信医药研发公司 | 2024-12-13 | — | — | CN | claimed |
| WO-2023196538-A1 | GPR35 MODULATORS AND USES THEREOF | CROSSIGNAL THERAPEUTICS, INC. (US) | 2023-10-12 | — | — | WO | claimed |
| CN-112851657-B | 3-hydroxyisothiazole derivative and preparation method and application thereof | 武汉工程大学 | 2022-10-21 | — | — | CN | claimed |
| CN-113122174-A | High-transparency mildew-proof silane modified polymer sealant and preparation method and application thereof | 吉和昌新材料(荆门)有限公司 | 2021-07-16 | — | — | CN | claimed |
| CN-112851657-A | 3-hydroxyisothiazole derivative and preparation method and application thereof | 武汉工程大学 | 2021-05-28 | — | — | CN | claimed |
| US-20210115087-A1 | CYCLIC PEPTIDE INHIBITORS OF HEDGEHOG PROTEINS | UNIV ROCHESTER (US) | 2021-04-22 | — | — | US | claimed |
| US-20190241615-A1 | CYCLIC PEPTIDE INHIBITORS OF HEDGEHOG PROTEINS | UNIVERSITY OF ROCHESTER | 2019-08-08 | — | — | US | claimed |
| WO-2019118612-A1 | TARGETING COMPOUNDS | ZAFGEN, INC. (US) | 2019-06-20 | — | — | WO | claimed |
| EP-3475294-A1 | CYCLIC PEPTIDE INHIBITORS OF HEDGEHOG PROTEINS | The University of Rochester (US) | 2019-05-01 | — | — | EP | claimed |
| EP-2223917-A1 | Isothiazolyloxyphenylamidines and their use as fungicides | Bayer CropScience AG (DE) | 2010-09-01 | — | — | EP | claimed |
| WO-2010086118-A1 | ISOTHIAZOLYLOXYPHENYL AMIDINES AND USE THEREOF AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2010-08-05 | — | — | WO | claimed |
| CN-101475790-A | Novel timber adhesive and preparation thereof | GUANG YANG (CN) | 2009-07-08 | — | — | CN | claimed |
| CN-101104996-A | Door sealing cushion ring for antibiotic mildew-resistant drum-type washing machine | HAIER GROUP (CN) | 2008-01-16 | — | — | CN | claimed |
| WO-2007138381-A2 | PHOSPHONATED OXAZOLIDINONES AND USES THEREOF FOR THE PREVENTION AND TREATMENT OF BONE AND JOINT INFECTIONS | TARGANTA THERAPEUTICS INC. (CA) | 2007-12-06 | — | — | WO | claimed |
| EP-1313717-B1 | OXAZOLYL-ARYLPROPIONIC ACID DERIVATIVES AND THEIR USE AS PPAR AGONISTS | LILLY CO ELI (US) | 2007-10-17 | — | — | EP | claimed |
| EP-0975611-A1 | 3-ALKOXY ISOTHIAZOLES | BAYER AG (DE) | 2000-02-02 | — | — | EP | claimed |
| WO-1998042689-A1 | 3-ALKOXY ISOTHIAZOLES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-10-01 | — | — | WO | claimed |
| EP-0542468-A1 | Isothiazolyl compounds and their use as microbicides | ROHM AND HAAS COMPANY (US) | 1993-05-19 | — | — | EP | claimed |
| US-4242495-A | COATINGS, MOLDINGS, FOAMS | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1980-12-30 | — | — | US | claimed |