Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 19/20 | 0.60 |
| ▸ | CNR2 | P34972 | 6/20 | 0.60 |
| ▸ | CCKAR | P32238 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27609514 | 0.85 | CNR1 (0.70) | CNR1CNR2 | |
| SCHEMBL28750942 | 0.84 | CNR1 (0.72) | CNR1CNR2 | |
| SCHEMBL27609619 | 0.84 | CNR1 (0.71) | CNR1CNR2 | |
| SCHEMBL5807509 | 0.83 | CNR1 (0.81) | CNR1CNR2 | |
| Hydrochloric Acid SCHEMBL27591195 | 0.82 | CNR1 (0.79) | CNR1CNR2 | |
| SCHEMBL3679902 | 0.80 | CNR1 (0.66) | CNR1CNR2 | |
| SCHEMBL27591365 | 0.79 | CNR1 (0.65) | CNR1CNR2 | |
| SCHEMBL27591293 | 0.77 | CNR1 (0.57) | CNR1CNR2 | |
| SCHEMBL27609778 | 0.77 | CNR1 (0.55) | CNR1CNR2 | |
| SCHEMBL675052 | 0.75 | CNR1 (1.00) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1865248-A | Imidazole-4-carboxamide derivatives, preparation and use thereof for treatment of obesity | BAYER PHARMACEUTICALS CORP (US) | 2006-11-22 | — | — | CN | disclosed |
| CN-1599724-A | Imidazole-4-carboxamide derivatives, their preparation and use in the treatment of obesity | BAYER PHARMACEUTICALS CORPORAT (US) | 2005-03-23 | — | — | CN | disclosed |