Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 12/20 | 0.52 |
| ▸ | PTPRC | P08575 | 1/20 | 0.43 |
| ▸ | PTPRG | P23470 | 1/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3816633 | 0.94 | LTB4R2 (0.44) | LTB4R2PTPRCPTPRG | |
| SCHEMBL28753492 | 0.92 | LTB4R2 (0.54) | LTB4R2AGTR1 | |
| SCHEMBL27610442 | 0.91 | LTB4R2 (0.55) | LTB4R2AGTR1 | |
| SCHEMBL3814752 | 0.90 | PTPRC (0.43) | PTPRCPTPRGPTGDR2 | |
| SCHEMBL27610388 | 0.86 | LTB4R2 (0.54) | LTB4R2AGTR1 | |
| SCHEMBL27592384 | 0.86 | LTB4R2 (0.44) | LTB4R2 | |
| SCHEMBL3815198 | 0.85 | PTPRC (0.45) | PTPRCPTPRG | |
| SCHEMBL2158402 | 0.85 | MAPT (0.41) | PTPRCPTPRG | |
| SCHEMBL2157641 | 0.85 | PTPRC (0.41) | LTB4R2PTPRCPTPRG | |
| SCHEMBL3811130 | 0.85 | LTB4R2 (0.47) | LTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100509797-C | Thiophene derivatives as antiviral agents against flavivirus infections | VIRUS CHEM PHARMA INC (CA) | 2009-07-08 | — | — | CN | claimed |
| CN-1602308-A | Thiophene derivatives as antiviral agents against flavivirus infections | VIRUS CHEM PHARMA INC (CA) | 2005-03-30 | — | — | CN | claimed |
| CN-101624391-A | Thiophene derivatives as antiviral agents for flavivirus infection | VIROCHEM PHARMA INC | 2010-01-13 | — | — | CN | disclosed |
| CN-100509797-C | Thiophene derivatives as antiviral agents against flavivirus infections | VIRUS CHEM PHARMA INC (CA) | 2009-07-08 | — | — | CN | disclosed |
| CN-1602308-A | Thiophene derivatives as antiviral agents against flavivirus infections | VIRUS CHEM PHARMA INC (CA) | 2005-03-30 | — | — | CN | disclosed |