Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL27610652

N.O=S(=O)(O)C(COCc1ccccc1)C(Cc1ccccc1)Cc1ccccc1

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CA1 P00915 5/20 0.44
CA2 P00918 3/20 0.44
CA7 P43166 3/20 0.44
CA9 Q16790 3/20 0.44
SLC1A1 P43005 1/20 0.41
TSHR P16473 2/20 0.41
CA4 P22748 1/20 0.40
MAPK1 P28482 1/20 0.40
TACR1 P25103 3/20 0.40
MAOB P27338 1/20 0.39
PPARG P37231 1/20 0.38
PPARA Q07869 1/20 0.38
ALDH1A1 P00352 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL27629674 0.82 PPARG (0.43) PPARGPPARA
SCHEMBL12444920 0.74 TSHR (0.50) CA1CA2CA7CA9TSHR
SCHEMBL12444919 0.74 TSHR (0.50) CA1CA2CA7CA9TSHR
SCHEMBL353816 0.73 ALPI (0.41) SLC1A1ALDH1A1
SCHEMBL22619569 0.72 CA1 (0.43) CA1CA2CA7CA9TSHR
Sulfuric Acid SCHEMBL21681660 0.72 TSHR (0.71) CA1CA2CA7CA9TSHR
SCHEMBL27610657 0.72 CA1 (0.47) CA1CA2CA7CA9SLC1A1
SCHEMBL27610658 0.72 CA1 (0.47) CA1CA2CA7CA9SLC1A1
Ammonia Solution, Strong SCHEMBL27610656 0.71 CSNK1E (0.50)
Sulfuric Acid SCHEMBL11103734 0.70 TSHR (0.68) CA1CA2CA7CA9TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100436409-C Derivative of substitutional taurine and preparation method UNIV BEIJING (CN) 2008-11-26 CN disclosed
CN-1696109-A Derivative of substitutional taurine and preparation method UNIV BEIJING (CN) 2005-11-16 CN disclosed