Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | LPAR3 | Q9UBY5 | 8/20 | 0.44 |
| ▸ | LPAR2 | Q9HBW0 | 6/20 | 0.44 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | CDC25A | P30304 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27611465 | 1.00 | TSHR (0.51) | TSHRLPAR3LPAR2LPAR1CYP3A4 | |
| SCHEMBL27611477 | 1.00 | TSHR (0.51) | TSHRLPAR3LPAR2LPAR1CYP3A4 | |
| SCHEMBL27630640 | 0.94 | TSHR (0.54) | TSHRLPAR3LPAR2LPAR1CYP3A4 | |
| SCHEMBL28193426 | 0.86 | TSHR (0.44) | TSHRTHRB | |
| SCHEMBL547333 | 0.83 | TSHR (0.44) | TSHRTHRB | |
| SCHEMBL6577522 | 0.82 | TSHR (0.54) | TSHRLPAR3LPAR2LPAR1CES2 | |
| SCHEMBL22401201 | 0.82 | TSHR (0.54) | TSHRLPAR3LPAR2LPAR1CES2 | |
| SCHEMBL21051160 | 0.82 | TSHR (0.54) | TSHRLPAR3LPAR2LPAR1CES2 | |
| SCHEMBL27785452 | 0.82 | TSHR (0.54) | TSHRLPAR3LPAR2LPAR1CES2 | |
| SCHEMBL18043472 | 0.82 | TSHR (0.54) | TSHRLPAR3LPAR2LPAR1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101322676-B | Dental coating kit | KURARAY MEDICAL INC | 2011-03-30 | — | — | CN | disclosed |
| CN-101322676-A | Dental coating kit | KURARAY MEDICAL INC (JP) | 2008-12-17 | — | — | CN | disclosed |
| CN-100415199-C | Dental coating kit | KURARAY MEDICAL INC (JP) | 2008-09-03 | — | — | CN | disclosed |
| CN-1703185-A | Dental coating kit | KURARAY MEDICAL INC (JP) | 2005-11-30 | — | — | CN | disclosed |