Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 5/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.49 |
| ▸ | USP7 | Q93009 | 1/20 | 0.44 |
| ▸ | IKBKB | O14920 | 1/20 | 0.42 |
| ▸ | CHUK | O15111 | 1/20 | 0.42 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | MYC | P01106 | 1/20 | 0.36 |
| ▸ | WDR5 | P61964 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27612570 | 0.85 | MAPT (0.53) | PIK3CGADORA2AADORA1MEN1KMT2A | |
| SCHEMBL27631651 | 0.85 | ADORA2A (0.54) | ADORA2AADORA1CHUKMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL28757234 | 0.83 | MAPT (0.51) | PIK3CGADORA2AADORA1MEN1KMT2A | |
| SCHEMBL4407006 | 0.81 | NPC1 (0.50) | ADORA2AADORA1MEN1KMT2A | |
| SCHEMBL27631713 | 0.81 | ADORA2A (0.51) | ADORA2AADORA1RPS6KA3MEN1KMT2A | |
| SCHEMBL27612323 | 0.81 | CSNK1A1 (0.55) | PIK3CGADORA2AADORA1SCN9A | |
| SCHEMBL27631860 | 0.80 | POLB (0.49) | ADORA2AKMT2AMAPT | |
| SCHEMBL21802136 | 0.80 | PIK3CG (0.47) | PIK3CGRPS6KA3 | |
| SCHEMBL1116418 | 0.80 | PIK3CG (0.60) | PIK3CGADORA2AADORA1IKBKBCHUK | |
| SCHEMBL27716588 | 0.79 | CSNK1A1 (0.53) | PIK3CGADORA2AADORA1SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1678321-A | Methods of treating or preventing autoimmune diseases with 2, 4-pyrimidinediamine compounds | RIGEL PHARMACEUTICALS INC (US) | 2005-10-05 | — | — | CN | disclosed |