Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 11/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.43 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.43 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27612789 | 0.90 | SYK (0.56) | SYKMAPTNPC1BRD4MAPK1 | |
| SCHEMBL27845992 | 0.85 | SYK (0.47) | SYKMAPK1HTTSIRT5XBP1 | |
| SCHEMBL27631810 | 0.85 | BRD4 (0.48) | SYKMAPTNPC1BRD4MAPK1 | |
| SCHEMBL654070 | 0.83 | SYK (0.63) | SYKBRD4MAPK1HTTSIRT5 | |
| SCHEMBL27612458 | 0.77 | SYK (0.59) | SYKMAPTBRD4MAPK1HTT | |
| SCHEMBL27631541 | 0.76 | SYK (0.54) | SYKBRD4MAPK1HTTSIRT5 | |
| SCHEMBL27839053 | 0.74 | SYK (0.53) | SYKMAPTBRD4MAPK1HTT | |
| SCHEMBL656203 | 0.73 | SYK (0.58) | SYKMAPTMAPK1HTTXBP1 | |
| SCHEMBL655819 | 0.72 | SYK (0.52) | SYKMAPTMAPK1HTTSIRT5 | |
| SCHEMBL7243040 | 0.72 | CDK4 (0.73) | MAPTNPC1SIRT5LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1678321-A | Methods of treating or preventing autoimmune diseases with 2, 4-pyrimidinediamine compounds | RIGEL PHARMACEUTICALS INC (US) | 2005-10-05 | — | — | CN | disclosed |