Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR | Q13258 | 20/20 | 0.77 |
| ▸ | TBXA2R | P21731 | 19/20 | 0.77 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.57 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.57 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.57 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.57 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.57 |
| ▸ | PTGFR | P43088 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1253026 | 0.87 | PTGDR (1.00) | PTGDRTBXA2RPTGER1PTGER3PTGER2 | |
| SCHEMBL2921193 | 0.85 | PTGDR (0.77) | PTGDRTBXA2RPTGER1PTGER3PTGER2 | |
| SCHEMBL992456 | 0.84 | PTGDR (1.00) | PTGDRTBXA2RPTGER1PTGER3PTGER2 | |
| SCHEMBL18269300 | 0.83 | PTGDR (0.84) | PTGDRTBXA2RPTGER1PTGER3PTGER2 | |
| SCHEMBL991172 | 0.78 | TBXA2R (1.00) | PTGDRTBXA2RPTGER1PTGER3PTGER2 | |
| SCHEMBL4322636 | 0.77 | PTGDR (0.78) | PTGDRTBXA2RPTGER1PTGER3PTGER2 | |
| SCHEMBL14621526 | 0.75 | PTGDR (0.84) | PTGDRTBXA2RPTGER1PTGER3PTGER2 | |
| SCHEMBL18269309 | 0.75 | PTGDR (0.67) | PTGDRTBXA2RPTGER1PTGER3PTGER2 | |
| SCHEMBL1253049 | 0.75 | PTGDR (0.59) | PTGDRTBXA2RPTGER1PTGER3PTGER2 | |
| SCHEMBL13668572 | 0.74 | PTGDR (0.79) | PTGDRTBXA2RPTGER1PTGER3PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1732171-A | Pyridopyrrolizine and pyridoindolizine derivatives | MERCK FROSST CANADA INC (CA) | 2006-02-08 | — | — | CN | disclosed |