Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 17/20 | 0.50 |
| ▸ | CDK1 | P06493 | 17/20 | 0.50 |
| ▸ | CCNB1 | P14635 | 17/20 | 0.50 |
| ▸ | CCNB3 | Q8WWL7 | 17/20 | 0.50 |
| ▸ | GSK3B | P49841 | 15/20 | 0.50 |
| ▸ | GSK3A | P49840 | 13/20 | 0.50 |
| ▸ | CDK5 | Q00535 | 10/20 | 0.44 |
| ▸ | CDK5R1 | Q15078 | 10/20 | 0.44 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1779800 | 0.94 | CCNB2 (0.52) | CCNB2CDK1CCNB1CCNB3GSK3B | |
| SCHEMBL1777955 | 0.87 | CCNB2 (0.54) | CCNB2CDK1CCNB1CCNB3GSK3B | |
| SCHEMBL1778264 | 0.82 | CCNB2 (0.47) | CCNB2CDK1CCNB1CCNB3GSK3B | |
| SCHEMBL1777165 | 0.67 | CCNB2 (0.56) | CCNB2CDK1CCNB1CCNB3GSK3B | |
| SCHEMBL27615789 | 0.66 | CCNB2 (0.60) | CCNB2CDK1CCNB1CCNB3GSK3B | |
| SCHEMBL1778829 | 0.63 | CCNB2 (0.69) | CCNB2CDK1CCNB1CCNB3GSK3B | |
| SCHEMBL7403498 | 0.61 | CYP4F2 (0.43) | — | |
| SCHEMBL1779137 | 0.61 | CDK1 (0.68) | CCNB2CDK1CCNB1CCNB3GSK3B | |
| SCHEMBL491029 | 0.61 | CCNB2 (1.00) | CCNB2CDK1CCNB1CCNB3GSK3B | |
| SCHEMBL1780235 | 0.60 | CCNB2 (0.73) | CCNB2CDK1CCNB1CCNB3GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100379734-C | Azaindoles | AVENTIS PHARMA LTD (GB) | 2008-04-09 | — | — | CN | disclosed |
| CN-1615873-A | Azaindoles compound | AVENTIS PHARMA LTD (GB) | 2005-05-18 | — | — | CN | disclosed |