Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 13/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | FLT1 | P17948 | 1/20 | 0.38 |
| ▸ | FLT4 | P35916 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | FRK | P42685 | 1/20 | 0.38 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.38 |
| ▸ | CCNC | P24863 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | BPTF | Q12830 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27632952 | 0.88 | CSF1R (0.36) | CSF1RRETPDGFRBKITSRC | |
| SCHEMBL906147 | 0.86 | CSF1R (0.41) | CSF1RRETPDGFRBKITSRC | |
| SCHEMBL5206065 | 0.85 | CSF1R (0.49) | CSF1RRETPDGFRBKITSRC | |
| SCHEMBL12056806 | 0.85 | CSF1R (0.42) | CSF1RRETPDGFRBKITSRC | |
| SCHEMBL12056807 | 0.84 | CDK2 (0.44) | CSF1RRETPDGFRBKITSRC | |
| SCHEMBL12056805 | 0.84 | CSF1R (0.43) | CSF1RRETPDGFRBKITSRC | |
| SCHEMBL12056812 | 0.81 | CSF1R (0.39) | CSF1RRETPDGFRBKITSRC | |
| SCHEMBL12065318 | 0.81 | CSF1R (0.52) | CSF1RRETPDGFRBKITSRC | |
| SCHEMBL28763820 | 0.80 | CSF1R (0.46) | CSF1RRETPDGFRBKITSRC | |
| SCHEMBL906176 | 0.80 | CSF1R (0.46) | CSF1RRETPDGFRBKITSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1726196-A | Pyrazine-based tubulin inhibitors | CYTOPIA PTY LTD (AU) | 2006-01-25 | — | — | CN | disclosed |