Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.71 |
| ▸ | TSHR | P16473 | 3/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.71 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.71 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.71 |
| ▸ | KDR | P35968 | 1/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.63 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.63 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.63 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cetyl Alcohol SCHEMBL9614341 | 0.88 | ESR1 (0.76) | ESR1TSHRALDH1A1CHRM1SLC6A2 | |
| Propylparaben SCHEMBL7200410 | 0.86 | ESR1 (0.89) | ESR1TSHRALDH1A1CHRM1SLC6A2 | |
| Propylparaben SCHEMBL6670652 | 0.86 | ESR1 (0.89) | ESR1TSHRALDH1A1CHRM1SLC6A2 | |
| Propylparaben SCHEMBL8102900 | 0.85 | ESR1 (0.93) | ESR1TSHRALDH1A1CHRM1SLC6A2 | |
| Propylparaben SCHEMBL429594 | 0.84 | ESR1 (1.00) | ESR1TSHRALDH1A1CHRM1SLC6A2 | |
| Propylparaben SCHEMBL977 | 0.84 | ESR1 (1.00) | ESR1TSHRALDH1A1CHRM1SLC6A2 | |
| Propylparaben SCHEMBL27533588 | 0.83 | ESR1 (0.89) | ESR1TSHRALDH1A1CHRM1SLC6A2 | |
| SCHEMBL10930012 | 0.83 | ESR1 (0.67) | ESR1TSHRALDH1A1CHRM1SLC6A2 | |
| Propylparaben SCHEMBL9406450 | 0.83 | ESR1 (0.96) | ESR1TSHRALDH1A1CHRM1SLC6A2 | |
| Propylparaben SCHEMBL1010568 | 0.83 | ESR1 (0.96) | ESR1TSHRALDH1A1CHRM1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8133877-B2 | Composition comprising an antisense sequence implicated in the regulation of angiogenesis | GENE SIGNAL INTERNATIONAL SA (CH) | 2012-03-13 | — | — | US | claimed |
| US-7803906-B2 | Composition comprising an angiogenesis related protein | GENE SIGNAL INTERNATIONAL SA (CH) | 2010-09-28 | — | — | US | claimed |
| US-20160304617-A1 | 5T4-TARGETED IMMUNOFUSION MOLECULE AND METHODS | ASANA BIOSCIENCES, LLC (US) | 2016-10-20 | — | — | US | disclosed |
| EP-3010939-A2 | 5T4-TARGETED IMMUNOFUSION MOLECULE AND METHODS | Asana BioSciences, LLC (US) | 2016-04-27 | — | — | EP | disclosed |
| WO-2014204988-A2 | 5T4-TARGETED IMMUNOFUSION MOLECULE AND METHODS | ASANA BIOSCIENCES, LLC (US) | 2014-12-24 | — | — | WO | disclosed |
| US-8133877-B2 | Composition comprising an antisense sequence implicated in the regulation of angiogenesis | GENE SIGNAL INTERNATIONAL SA (CH) | 2012-03-13 | — | — | US | disclosed |
| US-20110104169-A1 | REGULATOR GENES OF ANGIOGENESIS, PHARMACEUTICAL PREPARATIONS CONTAINING THEM AND THEIR APPLICATIONS | GENE SIGNAL INTERNATIONAL (CH) | 2011-05-05 | — | — | US | disclosed |
| US-7803906-B2 | Composition comprising an angiogenesis related protein | GENE SIGNAL INTERNATIONAL SA (CH) | 2010-09-28 | — | — | US | disclosed |
| US-20090264364-A1 | GENES IMPLICATED IN THE REGULATION OF ANGIOGENESIS, PHARMACEUTICAL PREPARATIONS CONTAINING THEM AND THEIR APPLICATIONS | GENE SIGNAL INTERNATIONAL, A CORPORATION OF SWITZERLAND (CH) | 2009-10-22 | — | — | US | disclosed |
| US-7553492-B2 | Gene overexpression/underexpression; antibodies; drug screening; kits | GENE SIGNAL (FR) | 2009-06-30 | — | — | US | disclosed |
| WO-2006055578-A2 | ASYMMETRIC SYNTHESIS OF (-)-AGELASTATIN A | TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEMS OF HIGHER EDUCATION (US) | 2006-05-26 | — | — | WO | disclosed |
| US-20050153917-A1 | Gene overexpression/underexpression; antibodies; drug screening; kits | GENE SIGNAL, A CORPORATION OF FRANCE (FR) | 2005-07-14 | — | — | US | disclosed |
| US-20050119215-A1 | Regulator genes of angiogenesis, pharmaceutical preparations containing them and their applications | GENE SIGNAL, A CORPORATION OF FRANCE (FR) | 2005-06-02 | — | — | US | disclosed |