Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | HPGD | P15428 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | STAT1 | P42224 | 1/20 | 0.49 |
| ▸ | DHFR | P00374 | 1/20 | 0.46 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | PI4KA | P42356 | 2/20 | 0.43 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.43 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.43 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5378064 | 0.90 | PI4KA (0.51) | ALDH1A1HPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL28283547 | 0.87 | SMN1; SMN2 (0.49) | ALDH1A1HPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL5172846 | 0.77 | PI4KA (0.46) | ALDH1A1SMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL12593291 | 0.74 | AVPR1A (0.67) | ALDH1A1HPGDSMN1; SMN2MEN1KMT2A | |
| SCHEMBL11978680 | 0.73 | MEN1 (0.50) | ALDH1A1HPGDSMN1; SMN2MEN1KMT2A | |
| SCHEMBL2620730 | 0.73 | AVPR1A (0.70) | ALDH1A1HPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL5173179 | 0.72 | CYP1A2 (0.41) | ALDH1A1HPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL12110445 | 0.72 | AVPR1A (0.73) | ALDH1A1HPGDSMN1; SMN2MEN1KMT2A | |
| SCHEMBL12247832 | 0.71 | MEN1 (0.49) | ALDH1A1HPGDSMN1; SMN2MEN1KMT2A | |
| SCHEMBL28001278 | 0.70 | PDPK1 (0.46) | ALDH1A1SMN1; SMN2NPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1723022-A | inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1 and type 2 | STERIX LTD (GB) | 2006-01-18 | — | — | CN | disclosed |